2-MONONITROGLYCERIN
Suppliers
Names
[ CAS No. ]:
620-12-2
[ Name ]:
2-MONONITROGLYCERIN
[Synonym ]:
2-Glyceryl mononitrate
2-nitrooxy-propane-1,3-diol
Glycerin 2-nitrate
2-mononitroglycerin
glycerol mononitrate
Glycerol-2-nitrate
Glyceryl 2-nitrate
1,2,3-Propanetriol,2-nitrate
Glycerol 2-mononitrate
Glycerol-2-nitrat
2-Mononitroglycerol
propylene glycol 2-nitrate
Chemical & Physical Properties
[ Density]:
1.48g/cm3
[ Boiling Point ]:
157.5ºC at 760 mmHg
[ Molecular Formula ]:
C3H7NO5
[ Molecular Weight ]:
137.09100
[ Flash Point ]:
49.1ºC
[ Exact Mass ]:
137.03200
[ PSA ]:
95.51000
[ Index of Refraction ]:
1.489
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MB0290000
- CHEMICAL NAME :
- Glycerol, 2-nitrate
- CAS REGISTRY NUMBER :
- 620-12-2
- BEILSTEIN REFERENCE NO. :
- 1765006
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C3-H7-N-O5
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,814,1986
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,814,1986
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >8 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,814,1986
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,814,1986
Safety Information
[ Symbol ]:
GHS02, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H302 + H332-H319
[ Precautionary Statements ]:
P210-P305 + P351 + P338
[ RIDADR ]:
UN 1648 3 / PGII
[ HS Code ]:
2920909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2920909090
[ Summary ]:
2920909090 esters of other inorganic acids of non-metals (excluding esters of hydrogen halides) and their salts; their halogenated, sulphonated, nitrated or nitrosated derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
Arzneimittelforschung 36(12) , 1752-6, (1986)
Comparative Hemodynamic Activity of Glyceryl 2-Nitrate and Glyceryl Trinitrate in Various Species and Pharmacokinetics of Glyceryl 2-Nitrate in Dog A single dose of glyceryl 2-nitrate (G-2-N) had prac...
Arzneimittelforschung 37(6) , 692-8, (1987)
Glyceryl 2-nitrate (G-2-N), which is the major metabolite of glyceryl trinitrate (GTN, Nitro Mack, glyceryl 1-nitrate (G-1-N) and isosorbide-5-nitrate (IS-5-N, Mono Mack) were examined in a comparativ...
Biotechnol. Appl. Biochem. 12(3) , 325-30, (1990)
Various microorganisms have been evaluated for their ability to hydrolyze glyceryl trinitrate (GTN) to glyceryl dinitrates and mononitrates. Provided that the GTN extracellular concentration was under...