Hyoscyamine sulfate hydrate
Suppliers
Names
[ CAS No. ]:
620-61-1
[ Name ]:
Hyoscyamine sulfate hydrate
[Synonym ]:
Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, sulfate, hydrate (2:1:1) (salt)
Atropina Solfato
UNII:03J5ZE7KA5
L-TROPINE TROPATE SULFATE
atropine sulphate
L-Hyoscyamine Hemisulfate
atropin sulfate
Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (αS)-, sulfate (2:1) (salt)
(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 3-hydroxy-2-phenylpropanoate sulfate hydrate (2:1:1)
Atropine Sulfate Monohydrate
MFCD00078244
(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 3-hydroxy-2-phenylpropanoate sulfate (2:1) hydrate (salt)
levsinsulfate
EINECS 210-644-6
Atropinsulfat
(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate sulfate (2:1)
L-HYOSCYAMINE SULFATE
Hyoscyamine sulfate hydrate
Chemical & Physical Properties
[ Melting Point ]:
205-206ºC
[ Molecular Formula ]:
C17H24NO5S0.5
[ Molecular Weight ]:
676.817
[ Exact Mass ]:
676.302979
[ PSA ]:
191.75000
[ LogP ]:
4.10130
[ Index of Refraction ]:
-28 ° (C=5, H2O)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YM6107000
- CAS REGISTRY NUMBER :
- 620-61-1
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C34-H46-N2-O6.H2-O4-S
- MOLECULAR WEIGHT :
- 676.90
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - infant
- DOSE/DURATION :
- 400 uL/kg/1D-I
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Cardiac - pulse rate increase, without fall in BP Skin and Appendages - dermatitis, other (after systemic exposure)
- REFERENCE :
- AJEMEN American Journal of Emergency Medicine. (WB Saunders, Philadelphia, PA) V.1- 1983- Volume(issue)/page/year: 15,532,1997
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - infant
- DOSE/DURATION :
- 800 uL/kg/1D-I
- TOXIC EFFECTS :
- Behavioral - irritability Cardiac - pulse rate increase, without fall in BP Skin and Appendages - dermatitis, other (after systemic exposure)
- REFERENCE :
- AJEMEN American Journal of Emergency Medicine. (WB Saunders, Philadelphia, PA) V.1- 1983- Volume(issue)/page/year: 15,532,1997
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - infant
- DOSE/DURATION :
- 400 uL/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Cardiac - pulse rate increase, without fall in BP Skin and Appendages - dermatitis, other (after systemic exposure)
- REFERENCE :
- AJEMEN American Journal of Emergency Medicine. (WB Saunders, Philadelphia, PA) V.1- 1983- Volume(issue)/page/year: 15,532,1997
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 210 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 55,849,1966 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80431 No. of Facilities: 967 (estimated) No. of Industries: 3 No. of Occupations: 9 No. of Employees: 3990 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80431 No. of Facilities: 445 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 14970 (estimated) No. of Female Employees: 12609 (estimated)
Safety Information
[ Risk Phrases ]:
R26/28
[ Safety Phrases ]:
S1;S45;S24/25
[ RTECS ]:
YM6107000