4-NITROPHENYL PHENYL ETHER

Names

[ CAS No. ]:
620-88-2

[ Name ]:
4-NITROPHENYL PHENYL ETHER

[Synonym ]:
EINECS 210-656-1
MFCD00007320
1-nitro-4-phenoxybenzene

Chemical & Physical Properties

[ Density]:
1.12g/cm3

[ Boiling Point ]:
320 °C(lit.)

[ Melting Point ]:
53-56 °C(lit.)

[ Molecular Formula ]:
C₁₂H₉NO₃

[ Molecular Weight ]:
215.20500

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
215.05800

[ PSA ]:
55.05000

[ LogP ]:
3.91030

[ Index of Refraction ]:
1.564

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KO2680000

CHEMICAL NAME :: Ether, 4-nitrophenyl phenyl

CAS REGISTRY NUMBER :: 620-88-2

BEILSTEIN REFERENCE NO. :: 2051911

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C12-H9-N-O3

MOLECULAR WEIGHT :: 215.22

WISWESSER LINE NOTATION :: WNR DOR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 100 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 67,123,1979

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
3077.0

[ WGK Germany ]:
3

[ RTECS ]:
KO2680000

[ Hazard Class ]:
9.0

[ HS Code ]:
2909309090

Precursor & DownStream

Precursor

1-Iodo-4-nitrobenzene
Phenol
1-Bromo-4-nitrobenzene
4-Chloronitrobenzene
1-Fluoro-4-nitrobenzene
4-Nitrophenol
Iodobenzene
Bromobenzene
POTASSIUMPHENOLATE
Fentin chloride

DownStream

4-phenoxyphenyl isothiocyanate
3-Phenoxybenzoic acid
1-Iodo-4-(4-nitrophenoxy)benzene
Benzene,1,1'-oxybis[2,4-dinitro- (9CI)
N-(4-phenoxyphenyl)nicotinamide
Bis(4-iodophenyl) ether
1-(4-Chlorophenoxy)-4-nitrobenzene
1-[4-(4-Nitrophenoxy)phenyl]ethanone
1-(4-Nitrophenyl)piperidine
1-Chloro-4-phenoxybenzene

Customs

[ HS Code ]: 2909309090

[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Mutagenicity of 4-nitrodiphenyl ether and its metabolites.

Toxicol. Lett. 34(1) , 13-21, (1986)

The mutagenic potential of 4-nitrodiphenyl ether (NDE) an intermediate of herbicides and an anthelmintic drug, and its reduced products (-NO, -NHOH) were investigated in the Ames test. All the three c...

Mutagenic activity of possible metabolites of 4-nitrobiphenyl ether.

Chem. Biol. Interact. 51(1) , 49-62, (1984)

A series of possible metabolites--4-nitrosobiphenyl ether (4-NO), 4-hydroxylaminobiphenyl ether (4-NHOH), 4-aminobiphenyl ether (4-NH2), 4-hydroxyacetylaminobiphenyl ether (4-N(OH)Ac), 4-acetoxyacetyl...

2-cyano-4-nitrophenyl phenyl ether
(4-nitrophenyl) phenyl sulfate
4-Nitrophenyl phenyl(trichloromethyl)phosphinate
(4-Nitrophenyl)(phenyl)methanone-d5
4-nitrophenyl phenyl disulfide
4-nitrophenyl phenyl phenylphosphoramidate
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methyl-2-(3-((4-((6-methyl-2-phenylpyridin-3-yl)oxy)pyridin-2-yl)amino)phenyl)propanoic acid
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
1,1-Dimethylethyl 4-(3,4-dihydro-3-oxo-1(2H)-quinoxalinyl)-1-piperidinecarboxylate
4-(4-{2-cyclopropylpyrazolo[1,5-a]pyrazin-4-yl}piperazin-1-yl)-N,N-dimethylpyrimidin-2-amine
6-chloro-2-[1-(3-methoxy-1-methyl-1H-pyrazole-4-carbonyl)piperidin-4-yl]-1,8-naphthyridine