Dirithromycin
Suppliers
Names
[ CAS No. ]:
62013-04-1
[ Name ]:
Dirithromycin
[Synonym ]:
(2R,3R,6R,7S,8S,9R,10R,12R,13S,15R,17S)-3-Ethyl-2,10-dihydroxy-15-[(2-methoxyethoxy)methyl]-2,6,8,10,12,17-hexamethyl-5-oxo-9-{[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy}-4,16-dio xa-14-azabicyclo[11.3.1]heptadec-7-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranoside
Noriclan
Dynabac
Dirythromycin
4,16-Dioxa-14-azabicyclo[11.3.1]heptadecan-5-one
MFCD00865041
ASE 136
4,16-Dioxa-14-azabicyclo[11.3.1]heptadecan-5-one, 7-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-3-ethyl-2,10-dihydroxy-15-[(2-methoxyethoxy)methyl]-2,6,8,10,12,17-hexamethyl-9- [[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3R,6R,7S,8S,9R,10R,12R,13S,15R,17S)-
Dirithomycin
Valodin
Dirithromycin
Antibiotic AS-E 136
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
871.8±65.0 °C at 760 mmHg
[ Melting Point ]:
185 - 189ºC
[ Molecular Formula ]:
C42H78N2O14
[ Molecular Weight ]:
835.074
[ Flash Point ]:
481.0±34.3 °C
[ Exact Mass ]:
834.545288
[ PSA ]:
196.33000
[ LogP ]:
2.84
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.533
[ Storage condition ]:
-20°C
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H317
[ Precautionary Statements ]:
P280
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R42/43
[ Safety Phrases ]:
S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
29419000
Customs
[ HS Code ]: 29419000
Articles
Ann. Pharmacother. 26(1) , 46-55, (1992)
To review the chemistry, antimicrobial spectrum, pharmacokinetics, clinical trials, adverse effects, and drug interactions of four new macrolide antibiotics: azithromycin, clarithromycin, dirithromyci...
J. Antimicrob. Chemother. 31 Suppl C , 65-75, (1993)
Dirithromycin is a new member of the macrolide class of antibiotics and has been developed for oral administration. Dirithromycin is a 14-membered lactone ring macrolide and is the C9-oxazine derivati...
J. Antimicrob. Chemother. 31 Suppl C , 51-64, (1993)
Polymorphonuclear neutrophils (PMN) play a prominent role in the host response to infectious diseases. One major bactericidal mechanism used by these cells is the production of reactive oxygen species...