3-(m-Tolyloxy)-1,2-propanediol

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Names

[ CAS No. ]:
621-24-9

[ Name ]:
3-(m-Tolyloxy)-1,2-propanediol

[Synonym ]:
3-m-Tolyloxy-propan-1,2-diol
3-m-tolyloxy-propane-1,2-diol
m-Mephenesin

Chemical & Physical Properties

[ Density]:
1.152g/cm3

[ Boiling Point ]:
354.7ºC at 760 mmHg

[ Molecular Formula ]:
C10H14O3

[ Molecular Weight ]:
182.21600

[ Flash Point ]:
168.3ºC

[ Exact Mass ]:
182.09400

[ PSA ]:
49.69000

[ LogP ]:
0.72700

[ Index of Refraction ]:
1.545

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TZ1200000
CHEMICAL NAME :
1,2-Propanediol, 3-(m-tolyloxy)-
CAS REGISTRY NUMBER :
621-24-9
BEILSTEIN REFERENCE NO. :
1948930
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H14-O3
MOLECULAR WEIGHT :
182.24
WISWESSER LINE NOTATION :
Q1YQ1OR C1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 72,1545,1952
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1474 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,470,1948

Related Compounds

  • 2-Methyl-3-(m-tolyloxy)-1,2-propanediol
  • 3-(4-Chloro-m-tolyloxy)-1,2-propanediol
  • 3-(6-isopropyl-m-tolyloxy)-1,2-Propanediol
  • (2S)-3-tolyloxy-1,2-propanediol acetonide
  • 3-(m-Butylphenoxy)-1,2-propanediol
  • 3-(m-Propylphenoxy)-1,2-propanediol
  • (2R)-4-(1H-1,2,3,4-tetrazol-1-yl)butan-2-ol
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 1H-Indole-1-ethanol, 2-methyl-3-(3-piperidinyl)-
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 7-(4-Aminophenyl)azepan-2-one
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde