Cbz-L-Prolinol

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Names

[ CAS No. ]:
6216-63-3

[ Name ]:
Cbz-L-Prolinol

[Synonym ]:
benzyl (2S)-2-(hydroxymethyl)pyrrolidine-1-carboxylate
Benzyl (2S)-2-(hydroxymethyl)-1-pyrrolidinecarboxylate
N-Cbz-L-prolinol
Cbz-L-Prolinol
1-Pyrrolidinecarboxylic acid, 2-(hydroxymethyl)-, phenylmethyl ester, (2S)-
N-benzyloxycarbonyl-L-prolinol
Z-L-Prolinol
Z-Prolinol
L-N-benzyloxycarbonylprolinol
MFCD02683224

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
382.0±25.0 °C at 760 mmHg

[ Molecular Formula ]:
C13H17NO3

[ Molecular Weight ]:
235.279

[ Flash Point ]:
184.8±23.2 °C

[ Exact Mass ]:
235.120850

[ PSA ]:
49.77000

[ LogP ]:
1.07

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.561

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Z-Pro-OH
  • Benzyl chloroformate
  • L-Pro-ol
  • Sulfuric acid
  • (S)-1-Benzyl 2-methyl pyrrolidine-1,2-dicarboxylate
  • N-(Benzyloxycarbonyloxy)succinimide
  • 2α-Formylpyrrolidine-1-carboxylic acid benzyl ester
  • Ethyl iodide
  • Dibenzyl dicarbonate
  • Proline

DownStream

  • L-Pro-ol
  • (S)-1-N-BOC-2-CYANO-PYRROLIDINE
  • (S)-1-Benzyl 2-methyl pyrrolidine-1,2-dicarboxylate
  • Boc-L- Prolinal
  • Boc-D-prolinal
  • (S)-1-Cbz-2-aminomethylpyrrolidine
  • Z-Pro-OH
  • (S)-BENZYL 2-(CYANOMETHYL)PYRROLIDINE-1-CARBOXYLATE
  • (S)-4-PHENYL-3-P-TOLYLOXAZOLIDIN-2-ONE

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • Cbz-L-Phe-OTfe
  • Cbz-L-Phe-L-Phe-NH2
  • Cbz-L-phenylalanine-L-proline methyl ester
  • CBZ-L-tert-Leucine isopropylamide salt
  • Cbz-L-Glu(Ome)-OtBu
  • Cbz-L-Ala-L-Ser-OH
  • 2-(4-Tert-butylphenyl)-4-(1-pyrrolidinyl)quinoline
  • 3-(3-chloro-4-methoxyphenyl)-N-(9H-fluoren-2-yl)propanamide
  • N-(5-(4-(isopropylsulfonyl)benzyl)-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide
  • N-[1-(4-Fluorophenyl)-2-methylpropyl]-3-methyl-2-thiophenemethanamine
  • 2-(4-Ethylphenyl)-4-(4-methyl-1-piperidinyl)quinoline
  • 5-(2-Bromophenyl)-N-(4-iodophenyl)-1,3,4-oxadiazole-2-methanamine
  • 1-[4-[[3-(2-Methylpropoxy)propyl]amino]-1-piperidinyl]ethanone
  • 3,5-Dibromo-2-ethoxy-N-[3-(2-methylpropoxy)propyl]benzenemethanamine
  • methyl (4R)-4-[(3R,5S,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-3,7,12-tris(trimethylsilyloxy)-2,3,4,5,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
  • 2-Ethyl-N-[(tetrahydro-2-furanyl)methyl]-3-benzofuranmethanamine