Cbz-L-Prolinol

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Names

[ CAS No. ]:
6216-63-3

[ Name ]:
Cbz-L-Prolinol

[Synonym ]:
benzyl (2S)-2-(hydroxymethyl)pyrrolidine-1-carboxylate
Benzyl (2S)-2-(hydroxymethyl)-1-pyrrolidinecarboxylate
N-Cbz-L-prolinol
Cbz-L-Prolinol
1-Pyrrolidinecarboxylic acid, 2-(hydroxymethyl)-, phenylmethyl ester, (2S)-
N-benzyloxycarbonyl-L-prolinol
Z-L-Prolinol
Z-Prolinol
L-N-benzyloxycarbonylprolinol
MFCD02683224

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
382.0±25.0 °C at 760 mmHg

[ Molecular Formula ]:
C13H17NO3

[ Molecular Weight ]:
235.279

[ Flash Point ]:
184.8±23.2 °C

[ Exact Mass ]:
235.120850

[ PSA ]:
49.77000

[ LogP ]:
1.07

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.561

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Z-Pro-OH
  • Benzyl chloroformate
  • L-Pro-ol
  • Sulfuric acid
  • (S)-1-Benzyl 2-methyl pyrrolidine-1,2-dicarboxylate
  • N-(Benzyloxycarbonyloxy)succinimide
  • 2α-Formylpyrrolidine-1-carboxylic acid benzyl ester
  • Ethyl iodide
  • Dibenzyl dicarbonate
  • Proline

DownStream

  • L-Pro-ol
  • (S)-1-N-BOC-2-CYANO-PYRROLIDINE
  • (S)-1-Benzyl 2-methyl pyrrolidine-1,2-dicarboxylate
  • Boc-L- Prolinal
  • Boc-D-prolinal
  • (S)-1-Cbz-2-aminomethylpyrrolidine
  • Z-Pro-OH
  • (S)-BENZYL 2-(CYANOMETHYL)PYRROLIDINE-1-CARBOXYLATE
  • (S)-4-PHENYL-3-P-TOLYLOXAZOLIDIN-2-ONE

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • Cbz-L-Phe-OTfe
  • Cbz-L-Phe-L-Phe-NH2
  • Cbz-L-phenylalanine-L-proline methyl ester
  • CBZ-L-tert-Leucine isopropylamide salt
  • Cbz-L-Glu(Ome)-OtBu
  • Cbz-L-Ala-L-Ser-OH
  • 2-(Aminomethyl)-6-iodo-4-isopropylphenol
  • Ethyl 3-(aminomethyl)-4-hydroxy-5-iodobenzoate
  • 2-(Aminomethyl)-6-chloro-4-ethoxyphenol
  • 2-(Aminomethyl)-4,6-dichloro-3-methylphenol
  • 2-(Aminomethyl)-4-chloro-3,6-dimethylphenol
  • 3-((2,2,2-Trifluoroethyl)amino)phenol
  • 2-(Aminomethyl)-4,6-dichloro-1,3-benzenediol
  • 6-(Aminomethyl)-4-chloro-2,3-dimethylphenol
  • 2-(Aminomethyl)-4,6-dichloro-3,5-dimethylphenol
  • 2-(Aminomethyl)-4,6-dibromo-3,5-dimethylphenol
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