p-tolylurea

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Names

[ CAS No. ]:
622-51-5

[ Name ]:
p-tolylurea

[Synonym ]:
p-tolylurea
p-methylphenylurea
p-Tolyurea
EINECS 210-739-2
MFCD00025433
4-methylphenylurea
p-Tolylcarbamide
4-Tolylurea
Urea,p-tolyl
p-Tolycarbamide

Chemical & Physical Properties

[ Density]:
1.192g/cm3

[ Boiling Point ]:
255.1ºC at 760 mmHg

[ Melting Point ]:
178-181 °C

[ Molecular Formula ]:
C8H10N2O

[ Molecular Weight ]:
150.17800

[ Flash Point ]:
108.1ºC

[ Exact Mass ]:
150.07900

[ PSA ]:
55.12000

[ LogP ]:
2.25890

[ Index of Refraction ]:
1.62

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YU4200000
CHEMICAL NAME :
Urea, p-tolyl-
CAS REGISTRY NUMBER :
622-51-5
BEILSTEIN REFERENCE NO. :
2208088
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H10-N2-O
MOLECULAR WEIGHT :
150.20
WISWESSER LINE NOTATION :
ZVMR D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
232 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic Behavioral - somnolence (general depressed activity)
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 54,188,1935 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
88 gm/kg/1Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Blood - lymphoma, including Hodgkin's disease
REFERENCE :
JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 3(5-6),149,1980

Safety Information

[ Risk Phrases ]:
33

[ Safety Phrases ]:
S24/25

[ RTECS ]:
YU4200000

[ HS Code ]:
2924299090

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • Butyl-p-tolylurea
  • 1,3-Di-p-tolylurea
  • Methyl-p-tolylurea
  • 1-butyl-3-p-tolylurea
  • N-Methyl-N'-p-tolylurea
  • 1-cyclohexyl-3-p-tolylurea
  • benzyl (2S,3S,4S,5R,6S)-3,4,5,6-tetraacetyloxyoxane-2-carboxylate
  • 2-Amino-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
  • (S)-3-Amino-4-isopropoxy-4-oxobutanoic acid
  • 1-[2-(2,4-Dichlorophenyl)-2-(thiophen-3-ylmethoxy)ethyl]imidazole
  • Tioconazole impurity C [EP]
  • (S)-N-((S)-2-Hydroxy-1,2,2-triphenylethyl)pyrrolidine-2-carboxamide
  • 4-Bromo-2-nitrophenyl Isothiocyanate
  • 4-(Di-p-tolylamino)benzoic acid
  • alpha-D-Glucose 6-Dihydrogen Phosphate 1,2,3,4-Tetraacetate
  • 5,6,7,8-Tetrahydro-4-methoxy-5,6-dimethyl-1,3-dioxolo[4,5-g]isoquinoline
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