4-Ethoxyphenol

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Names

[ CAS No. ]:
622-62-8

[ Name ]:
4-Ethoxyphenol

[Synonym ]:
Phenol,p-ethoxy
p-ethoxylphenol
4-Hydroxyphenetole
Phenol,4-ethoxy
1-hydroxy-4-ethoxybenzene
P-ETHOXYPHENOL
4-Ethoxybenzolol
EINECS 210-748-1
Hydroquinone monoethyl ether
4-Ethoxyphenol
Phenol, 4-ethoxy-
4-(ethyloxy)phenol
p-Hydroxyphenetole
MFCD00002334
4-ethoxy-phenol
Ethoxyphenol,p

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
246.4±13.0 °C at 760 mmHg

[ Melting Point ]:
64-67 °C

[ Molecular Formula ]:
C8H10O2

[ Molecular Weight ]:
138.164

[ Flash Point ]:
124.0±4.8 °C

[ Exact Mass ]:
138.068085

[ PSA ]:
29.46000

[ LogP ]:
1.84

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.527

[ Water Solubility ]:
slightly soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SL3790000
CHEMICAL NAME :
Phenol, p-ethoxy-
CAS REGISTRY NUMBER :
622-62-8
BEILSTEIN REFERENCE NO. :
1907114
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C8-H10-O2
MOLECULAR WEIGHT :
138.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RBPMAZ Revue Belge de Pathologie et de Medecine Experimentale. (Brussels, Belgium) V.18-31, 1947-65. For publisher information, see PTEUA6. Volume(issue)/page/year: 22,1,1952 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
667 mg/kg
SEX/DURATION :
female 11 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 41,43,1990

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R37/38;R41

[ Safety Phrases ]:
S37/39-S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
SL3790000

[ HS Code ]:
2909500000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-ethoxyphenyl benzyl ether
  • 4-ethoxyanisole
  • 4-Ethoxyphenylboronic acid
  • Ethanol
  • 1,4-Benzoquinone
  • 4-Ethoxybenzaldehyde
  • Bromoethane
  • Hydroquinone
  • phenetole
  • Ethyl iodide

DownStream

  • 4-ethoxycyclohexan-1-ol
  • 2-[(4-ethoxyphenoxy)methyl]oxirane
  • Hydroquinone
  • 4β-Ethoxycyclohexanone
  • 4-Ethoxyphenyl 4-Butylbenzoate
  • 4H-1-BENZOPYRAN-4-ONE, 6-ETHOXY-2,3-DIHYDRO-
  • 4-ethoxy-4-methoxycyclohexa-2,5-dien-1-one
  • 4-Ethoxyphenol dimethylcarbamate
  • 4-Ethoxyphenyl trans-4-Butylcyclohexanecarboxylate
  • 5-ethoxy-2-hydroxy-benzaldehyde

Customs

[ HS Code ]: 2909500000

[ Summary ]:
2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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Related Compounds

  • 2-ALLYL-4-ETHOXYPHENOL
  • 3-Amino-4-ethoxyphenol
  • 2-Bromo-4-ethoxyphenol
  • 3-fluoro-4-ethoxyphenol
  • 3-Chloro-4-ethoxyphenol
  • 4-ethoxyphenol,formic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • N-(2-fluorophenyl)-2-methyl-5-(2-phenylethenesulfonamido)benzene-1-sulfonamide
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide