chloro-(4-hydroxyphenyl)mercury

Names

[ CAS No. ]:
623-07-4

[ Name ]:
chloro-(4-hydroxyphenyl)mercury

[Synonym ]:
p-Hydroxyphenylmercury chloride
4-Chloromercuriphenol
p-HOC6H4HgCl
4-chloromercuriophenol
p-Chloromercuriphenol
4-Hydroxyphenylmercuric chloride
p-hydroxyphenylmercuric chloride

Chemical & Physical Properties

[ Molecular Formula ]:
C6H5ClHgO

[ Molecular Weight ]:
329.14600

[ Exact Mass ]:
329.97400

[ PSA ]:
20.23000

[ LogP ]:
1.25380

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OW0525000
CHEMICAL NAME :
Mercury, chloro(p-hydroxyphenyl)-
CAS REGISTRY NUMBER :
623-07-4
BEILSTEIN REFERENCE NO. :
3662178
LAST UPDATED :
199712
DATA ITEMS CITED :
24
MOLECULAR FORMULA :
C6-H5-Cl-Hg-O
MOLECULAR WEIGHT :
329.15
WISWESSER LINE NOTATION :
QR D-HG-G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,31,1953
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,36,1953
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
55 mg/kg
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 31,87,1927 *** REVIEWS *** ACGIH TLV-TWA 0.1 mg(Hg)/m3 (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.05 mg(Hg)/m3 DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8. Volume(issue)/page/year: 3,22,1973 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.05 mg(Hg)/m3;Skin JAN 1993 OEL-BELGIUM:TWA 0.05 mg(Hg)/m3;Skin JAN 1993 OEL-DENMARK:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-FINLAND:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-FRANCE:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-GERMANY:TWA 0.01 ppm (0.1 mg(Hg)/m3) JAN 1993 OEL-HUNGARY:TWA 0.02 mg(Hg)/m3;STEL 0.04 mg(Hg)/m3 JAN 1993 OEL-JAPAN:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.05 mg(Hg)/m3;STEL 0.15 mg(Hg)/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-POLAND:TWA 0.01 mg(Hg)/m3 JAN 1993 OEL-RUSSIA:TWA 0.05 mg(Hg)/m3;STEL 0.01 mg(Hg)/m3 JAN 1993 OEL-SWEDEN:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-THAILAND:STEL 0.05 mg(Hg)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.05 mg(Hg)/m3;STEL 0.15 mg(Hg)/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO MERCURY, ARYL AND INORGANIC-air:CL 0.1 mg/m3 (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992

Synthetic Route

Precursor & DownStream

Precursor

  • Phenol
  • POTASSIUMPHENOLATE

DownStream

  • 4-Fluorophenol
  • 4-Nitrosophenol

Related Compounds

  • M-AZOTOLUENE
  • chloro-(3,5-ditert-butyl-4-hydroxyphenyl)mercury
  • chloro(hydroxyphenyl)mercury
  • (3-chloro-4-hydroxyphenyl) octanoate
  • (3-chloro-4-hydroxyphenyl)-(1-chloro-2-phenylindolizin-3-yl)methanone
  • (3-chloro-4-hydroxyphenyl) acetate
  • 4-(4-Chloro-phenylamino)-7-methoxy-quinazolin-6-ol
  • 4-(Bromophenylmethyl)tetrahydro-2H-pyran
  • 2-(4-Fluorobenzyl)benzyl bromide
  • N,N-Dimethyl-3-nitro-4-pyridinecarboxamide
  • 4-((4-Bromo-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate
  • 4-Nitrothiophene-2-sulfonamide
  • 3-(2-(4-methylphenylsulfonamido)thiazol-4-yl)-N-(thiophen-2-ylmethyl)propanamide
  • 3-[2-(4-methylbenzenesulfonamido)-1,3-thiazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]propanamide
  • N-(benzo[d][1,3]dioxol-5-yl)-3-(2-(4-methylphenylsulfonamido)thiazol-4-yl)propanamide
  • Methyl 2-amino-3-(1,3-thiazol-5-yl)propanoate
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