Benzene-1,4-diammonium chloride

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Names

[ CAS No. ]:
624-18-0

[ Name ]:
Benzene-1,4-diammonium chloride

[Synonym ]:
1,4-Benzenediamine dihydrochloride
Benzene-1,4-diamine dihydrochloride
EINECS 210-834-9
1,4-Benzenediamine, hydrochloride (1:2)
benzene-1,4-diamine,dihydrochloride
Benzol-1,4-diamindihydrochlorid
MFCD00013002

Chemical & Physical Properties

[ Density]:
1.15 g/cm3

[ Boiling Point ]:
267.4ºC at 760 mmHg

[ Melting Point ]:
>200°C

[ Molecular Formula ]:
C6H10Cl2N2

[ Molecular Weight ]:
181.063

[ Flash Point ]:
135.9ºC

[ Exact Mass ]:
180.022110

[ PSA ]:
52.04000

[ LogP ]:
3.61740

[ Water Solubility ]:
>=10 g/100 mL at 21 ºC

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ST0350000
CHEMICAL NAME :
p-Phenylenediamine, dihydrochloride
CAS REGISTRY NUMBER :
624-18-0
LAST UPDATED :
199710
DATA ITEMS CITED :
19
MOLECULAR FORMULA :
C6-H8-N2.2Cl-H
MOLECULAR WEIGHT :
181.08
WISWESSER LINE NOTATION :
ZR DZ &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
147 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
316 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
Specific locus test

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - mouse Lymphocyte
DOSE/DURATION :
1250 ug/L
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 12(Suppl 13),103,1988 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,125,1978

Safety Information

[ Symbol ]:

GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H311-H317-H319-H331-H410

[ Precautionary Statements ]:
P261-P273-P280-P301 + P310-P305 + P351 + P338-P311

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic

[ Risk Phrases ]:
R23/24/25;R36;R43;R50/53

[ Safety Phrases ]:
S28-S36/37-S45-S60-S61-S28A

[ RIDADR ]:
UN 1673 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
ST0350000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
29215119

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Hydrochloric acid
  • N-(4-ISOTHIOCYANATO-PHENYL)-ACETAMIDE

DownStream

  • Wurster's blue
  • P-DINITROBENZENE
  • h3b*nh2c6h4-4-nh2*bh3
  • 4'-Aminobenzanilide
  • Benzamide, N,N-1,4-phenylenebis-
  • 1,4-(2H4)Benzenediamine
  • N-(2-Aminoethyl)-1,4-benzenediamine
  • 1-N,1-N,4-N,4-N-tetraethylbenzene-1,4-diamine
  • 2-[4-(diaminomethylideneamino)phenyl]guanidine
  • 4-chloro-N-[4-(4-chlorobutylsulfonylamino)phenyl]butane-1-sulfonamide

Customs

[ HS Code ]: 2921519090

[ Summary ]:
2921519090. o-, m-, p-phenylenediamine, diaminotoluenes, and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:17.0%. . MFN tariff:6.5%. General tariff:30.0%

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Related Compounds

  • benzene-1,4-diammonium bis(4-methylbenzenesulphonate)
  • benzene-1,4-dicarbonyl chloride,carbonyl dichloride,4-[2-(4-hydroxyphenyl)propan-2-yl]phenol
  • benzene-1,4-disulfonyl chloride
  • benzene-1,4-diamine,benzene-1,4-dicarbonyl chloride
  • benzene-1,4-didiazonium,dichloride
  • Benzene,1-(4-chlorobutoxy)-4-methyl-