1,2-Difluoroethane

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Names

[ CAS No. ]:
624-72-6

[ Name ]:
1,2-Difluoroethane

[Synonym ]:
1,2-difluoroethane
MFCD00039286

Chemical & Physical Properties

[ Density]:
0.913 g/cm3

[ Boiling Point ]:
31ºC

[ Molecular Formula ]:
C2H4F2

[ Molecular Weight ]:
66.05000

[ Exact Mass ]:
66.02810

[ LogP ]:
0.92540

[ Index of Refraction ]:
1.254

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KI1410500
CHEMICAL NAME :
Ethane, 1,2-difluoro-
CAS REGISTRY NUMBER :
624-72-6
BEILSTEIN REFERENCE NO. :
1730859
LAST UPDATED :
199806
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C2-H4-F2
MOLECULAR WEIGHT :
66.06

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
75 ppm/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
977 gm/m3/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1000 ppm/20M/5D-I
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Related to Chronic Data - death
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3000 ppm/20M/3D-I
TOXIC EFFECTS :
Related to Chronic Data - death

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
50 pph/72H (Continuous)
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 72,15,1984

Safety Information

[ Hazard Codes ]:
T: Toxic;F: Flammable;

[ Risk Phrases ]:
R12

[ Safety Phrases ]:
3/7-9-16-33

[ RIDADR ]:
UN 3161

[ HS Code ]:
2903399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1,2-bis(tosyloxy)ethane
  • 2-Fluoroethyl 4-methylbenzenesulfonate
  • 1,2-Dibromoethane
  • Ethylene glycol
  • ethene
  • 1,2-Diiodoethane
  • Xenon difluoride
  • dichloroethane
  • 1-Bromo-2-fluoroethane
  • 2-Fluoroethanol

DownStream

  • Carbon tetrafluoride
  • Pentafluoroethane
  • perfluoropropane
  • 1,1,2,2-tetrafluoroethane
  • 1,2-dichloro-1,2-difluoroethane
  • 1,2-Difluoro-1,1,2-trichloroethane
  • 1,2-difluorotetrachloroethane
  • 1-chloro-1,2-difluoroethane
  • 1,1-Dichloro-1,2-difluoroethane
  • Ethylene glycol

Customs

[ HS Code ]: 2903399090

[ Summary ]:
2903399090. brominated,fluorinated or iodinated derivatives of acyclic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Related Compounds

  • 1-chloro-1,2-difluoroethane
  • 1,2-dibromo-1,2-difluoroethane
  • 1,2-dichloro-1,2-difluoroethane
  • 1,1-Dichloro-1,2-difluoroethane
  • 1,1,2-trichloro-1,2-difluoroethane
  • 1,1,2,2-tetrachloro-1,2-difluoroethane
  • Benzyl 3-benzoylpiperidine-1-carboxylate
  • 3,6-Diamino-1,2-benzisothiazole-7-carboxamide
  • 5-(2-methylbutyl)-4-phenyl-4H-1,2,4-triazole-3-thiol
  • Tert-butyl (6-(6-acetylpyridin-2-yl)-2-(6-methylpyridin-2-yl)-2H-indazol-4-yl)carbamate
  • (S)-2-(pyridin-2-yl)propyl methanesulfonate
  • N-(4-(5-Chloro-2-(difluoromethoxy)phenyl)-2-(4-((2-cyanoethyl)(methyl)amino)piperidin-1-yl)thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
  • Na(2)-(2,5-Difluorophenyl)-N,N-dimethylurea
  • 5-Methyl-2-[(trifluoroacetamido)methyl]-1,3-thiazole-4-carboxylic acid
  • 3-(dimethylamino)-N-[2-(dimethylamino)ethyl]-N-methylpropanamide
  • 7-methoxy-N-methyl-3-Quinolinecarboxamide
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