5,6-Dihydro-5-azacytidine hydrochloride

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Names

[ CAS No. ]:
62402-31-7

[ Name ]:
5,6-Dihydro-5-azacytidine hydrochloride

Chemical & Physical Properties

[ Density]:
2.1g/cm3

[ Boiling Point ]:
539.6ºC at 760 mmHg

[ Molecular Formula ]:
C8H15ClN4O5

[ Molecular Weight ]:
282.68200

[ Flash Point ]:
280.2ºC

[ Exact Mass ]:
282.07300

[ PSA ]:
140.64000

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XZ3018600
CHEMICAL NAME :
1,3,5-Triazin-2(1H)-one, 5,6-dihydro-4-amino-1-beta-D-ribofuranosyl-, monohydrochloride
CAS REGISTRY NUMBER :
62402-31-7
LAST UPDATED :
199409
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H14-N4-O5.Cl-H
MOLECULAR WEIGHT :
282.72

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2559 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB82-195751
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
INNDDK Investigational New Drugs. The Journal of New Anticancer Agents. Kluwer Academic Pub., POB 358, Accord Stn., Hingham, MA 02018) V.1- 1983- Volume(issue)/page/year: 1,47,1983

Related Compounds

  • Dihydro-5-azacytidine
  • 5,6-Dihydro-5,12:6,11-di-o-benzenodibenzo[a,e]cyclooctene
  • 5,6-Dihydro-5-methyl-11-oxo-11H-dibenz[b,e]azepine-2-carbaldehyde
  • 5,6-Dihydro-5-methyluracil-d6
  • 5,6-Dihydro-5-diazopyrimidine-2,4(1H,3H)-dione
  • 5,6-dihydro-5,6-dihydroxy-y,y-Carotene
  • 2-(Iodomethyl)-5-phenyloxolane
  • Urea,n-(imidazo[1,2-a]pyridin-2-ylmethyl)-n'-(1-methyl-4-piperidinyl)-
  • 1-(2-Phenyl-quinolin-7-yl)-3-piperidin-4-ylmethyl-imidazo[1,5-a]pyrazin-8-ylamine
  • 2-(1,1-Dimethylethyl)imidazo[1,2-b]pyridazin-6-amine
  • 1,3-Benzenediamine, 4-ethyl-2-methyl-6-(methylthio)-
  • N-{5-[(4-Chlorophenyl)(ethyl)sulfamoyl]-1,3,4-thiadiazol-2-YL}-2-methylpropanamide
  • 4-(4'-Iodobiphenyl-4-yl)-2-methylbut-3-yn-2-ol
  • 2-({3-[2-(1H-indol-3-yl)ethyl]-4-oxo-3,4-dihydropteridin-2-yl}sulfanyl)-N-(4-methylphenyl)acetamide
  • N-(3,4-dimethylphenyl)-2-({3-[2-(1H-indol-3-yl)ethyl]-4-oxo-3,4-dihydropteridin-2-yl}sulfanyl)acetamide
  • 2-({3-[2-(1H-indol-3-yl)ethyl]-4-oxo-3,4-dihydropteridin-2-yl}sulfanyl)-N-(2,4,6-trimethylphenyl)acetamide
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