3-Hydroxyisovaleric acid

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Names

[ CAS No. ]:
625-08-1

[ Name ]:
3-Hydroxyisovaleric acid

[Synonym ]:
MFCD00059081
Beta-Hydroxyisovaleric Acid
3-hydroxy-3-methylbutanoic acid

Chemical & Physical Properties

[ Density]:
0.938 g/mL at 25 °C(lit.)

[ Boiling Point ]:
88 °C1 mm Hg(lit.)

[ Melting Point ]:
−80 °C(lit.)

[ Molecular Formula ]:
C5H10O3

[ Molecular Weight ]:
118.13100

[ Flash Point ]:
113 °C

[ Exact Mass ]:
118.06300

[ PSA ]:
57.53000

[ LogP ]:
0.23200

[ Index of Refraction ]:
n20/D 1.4415(lit.)

[ Storage condition ]:
Refrigerator

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
UN 3334

[ WGK Germany ]:
3

[ HS Code ]:
2918199090

Synthetic Route

Precursor & DownStream

Precursor

  • 4-Hydroxy-4-methyl-2-pentanone
  • 2,2-Dimethyloxetane-4-one
  • tert-Butanol
  • 2-METHYL-4-PENTEN-2-OL
  • Ketoleucine
  • 3,3-Dimethylacrylic acid
  • PERCHLORIC ACID
  • 3-Methylbutanoic acid
  • (±)-4-methyl-1,2,4-pentanetriol
  • tert-butyl 3-hydroxy-3-methylbutyrate

DownStream

  • 3,3-Dimethylacrylic acid
  • tert-Butanol
  • ethyl 3-hydroxy-3-methylbutyrate
  • Methyl-3-hydroxy-3-methylbutanoate

Customs

[ HS Code ]: 2918199090

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.

J. Nutr. 144(12) , 1977-84, (2014)

Biotin functions as a cofactor for several carboxylase enzymes with key roles in metabolism. At present, the dietary requirement for biotin is unknown and intake recommendations are provided as Adequa...

HMDB: a knowledgebase for the human metabolome.

Nucleic Acids Res. 37(Database issue) , D603-10, (2009)

The Human Metabolome Database (HMDB, http://www.hmdb.ca) is a richly annotated resource that is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, ...

Age-related reference values for urinary organic acids in a healthy Turkish pediatric population.

Clin. Chem. 40(6) , 862-6, (1994)

Organic acid concentrations were quantified by gas chromatography and the individual acids identified by mass spectrometry in urine specimens from a healthy Turkish pediatric population of ages 2 days...


More Articles


Related Compounds

  • 3-hydroxyisovaleric acid
  • 2-oxo-3-hydroxyisovaleric acid
  • 2-ACETOXY-3-METHYL-BUTYRIC ACID
  • D-α-HYDROXYISOVALERIC ACID
  • (±)-2-hydroxy-3-methylbutyric acid
  • 2-Hydroxy-3-methylbutyric acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • N-(4-bromo-2-(2-chlorobenzoyl)phenyl)-4-(N,N-dipropylsulfamoyl)benzamide
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • Imidazo[1,2-a]pyridine,2-[[2-(2,5-difluorophenyl)-1h-imidazol-1-yl]methyl]-3-ethyl-6-fluoro-
  • tert-Butyl-DL-alanine