Ethylurea

Names

[ CAS No. ]:
625-52-5

[ Name ]:
Ethylurea

[Synonym ]:
urea,ethyl
monoethylurea
MFCD00007953
N-ETHYLUREA
EINECS 210-898-8
ethyl-ure
ETHANOLUREA
1-ethyl-ure
ethvlurea

Chemical & Physical Properties

[ Density]:
1.005 g/cm3

[ Boiling Point ]:
136.3ºC at 760 mmHg

[ Melting Point ]:
87-90 °C(lit.)

[ Molecular Formula ]:
C₃H₈N₂O

[ Molecular Weight ]:
88.10840

[ Flash Point ]:
93 °C

[ Exact Mass ]:
88.06370

[ PSA ]:
55.12000

[ LogP ]:
0.76580

[ Water Solubility ]:
soluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YT2335000

CHEMICAL NAME :: Urea, ethyl-

CAS REGISTRY NUMBER :: 625-52-5

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C3-H8-N2-O

MOLECULAR WEIGHT :: 88.13

WISWESSER LINE NOTATION :: ZVM2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6610 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2 gm/kg

SEX/DURATION :: female 10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Protozoa - Chlamydomonas reinhardi

DOSE/DURATION :: 400 mmol/L

REFERENCE :: FOMIAZ Folia Microbiologica (Prague). (Academia, Vodickova 40, 112 29 Prague 1, Czechoslavakia) V.4- 1959- Volume(issue)/page/year: 20,452,1975

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R68

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
1325

[ WGK Germany ]:
3

[ RTECS ]:
YT2335000

[ Packaging Group ]:
III

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

S-methyl N-ethylcarbamothioate
N-Nitrocarbamide
Ethylamine
Ethyl isocyanate
Isothiocyanatoethane
NETHYLNNITROGUANIDINE
N-Nitroso-N-methylurea
(2-hydroxyphenyl) carbamate
Ethyl allophanate

DownStream

n-ethylphthalimide
6-amino-1-ethylpyrimidine-2,4-dione
2-CHLORO-N-[(ETHYLAMINO)CARBONYL]-2-PHENYLACETAMIDE
Potassium cyanate
Ethylamine
Ethylhydrazine oxalate
1-ethylimidazolidine-2,4,5-trione
N-NITROSO-N-ETHYLUREA
Ethyl isocyanate
1,5,5-triethyl-1,3-diazinane-2,4,6-trione

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Solvation of human serum albumin in aqueous alkylurea solutions.

Int. J. Pept. Protein Res. 42(4) , 320-5, (1993)

Solvation of human serum albumin in aqueous solutions of urea, methyl-, N,N'-dimethyl-, and ethylurea was studied by density measurements. From the densities at constant molality and constant chemical...

Inhibition of HIV-1 infection by alkylureas.

AIDS 5(12) , 1447-52, (1991)

The risk of infection by HIV-1 through transfusion of contaminated blood products has been markedly decreased but not eliminated by serological screening of donors. Methods are required to further min...

Neoplasia induced in male rats fed lead acetate, ethyl urea, and sodium nitrite.

Toxicol. Pathol. 13(1) , 50-7, (1985)

Sprague-Dawley rats were exposed to 0, 26, or 2600 ppm lead as lead acetate in drinking water for 76 weeks. At 28 weeks of lead exposure, a portion of each group was exposed simultaneously to 6.36 g/k...

Nitrosoethylurea
ethylurea hydrazide
1-butyl-3-ethylurea
1-butyl-1-ethylurea
1-ethyl-3-methylurea
N-allyl-N'-ethylurea