(2R)-2-(3-chloro-4-methylsulfonylphenyl)-3-[(1R)-3-oxocyclopentyl]-N-pyrazin-2-ylpropanamide

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Names

[ CAS No. ]:
625114-41-2

[ Name ]:
(2R)-2-(3-chloro-4-methylsulfonylphenyl)-3-[(1R)-3-oxocyclopentyl]-N-pyrazin-2-ylpropanamide

[Synonym ]:
Piragliatin

Chemical & Physical Properties

[ Molecular Formula ]:
C19H20ClN3O4S

[ Molecular Weight ]:
421.89800

[ Exact Mass ]:
421.08600

[ PSA ]:
117.96000

[ LogP ]:
4.74540

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Aminopyrazine
  • (R)-2-(3-chloro-4-methanesulfonyl-phenyl)-3-((R)-3-oxo-cyclopentyl)-propionyl chloride
  • (2R)-2-(3-chloro-4-methanesulfonylphenyl)-3-[(1R)-3-oxocyclopentyl]propanoic acid
  • 2-Chlorothiosanisole
  • Cyclopentenone
  • (3-chloro-4-methylsulfanyl-phenyl)-oxo-acetic acid methyl ester
  • [3-Chloro-4-(methylsulfanyl)phenyl]acetic acid
  • (3-chloro-4-methylsulfanyl-phenyl)-N-[2(R)-hydroxy-1(R)-methyl-2(R)-phenyl-ethyl]-N-methyl acetamide

DownStream