5-fluoro-7-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline

Names

[ CAS No. ]:
625127-11-9

[ Name ]:
5-fluoro-7-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline

[Synonym ]:
intermediate 7
5-fluoro-7-trifluoromethyl-1,2,3,4-tetrahydro-isoquinoline

Chemical & Physical Properties

[ Molecular Formula ]:
C10H9F4N

[ Molecular Weight ]:
219.17900

[ Exact Mass ]:
219.06700

[ PSA ]:
12.03000

[ LogP ]:
2.81900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2,2,2-trifluoro-1-(5-fluoro-7-trifluoromethyl-3,4-dihydro-1H-isoquinolln-2-yI)-ethanone
  • 2,2,2-trifluoro-N-[2-(2-fluoro-4-trifluoromethyl-phenyl)-ethyl]-acetamide

DownStream

Related Compounds

  • N-(4-methoxybenzyl)-6-(8-oxo-6-((2-oxo-2-phenylethyl)thio)-[1,3]dioxolo[4,5-g]quinazolin-7(8H)-yl)hexanamide
  • 6-(6-((2-(4-fluorophenyl)-2-oxoethyl)thio)-8-oxo-[1,3]dioxolo[4,5-g]quinazolin-7(8H)-yl)-N-(4-methoxybenzyl)hexanamide
  • 6-(6-((2-(4-chlorophenyl)-2-oxoethyl)thio)-8-oxo-[1,3]dioxolo[4,5-g]quinazolin-7(8H)-yl)-N-(4-methoxybenzyl)hexanamide
  • 6-[6-[(2-fluorobenzyl)thio]-8-oxo[1,3]dioxolo[4,5-g]quinazolin-7(8H)-yl]-N-(4-methoxybenzyl)hexanamide
  • 6-(6-{[(3-fluorophenyl)methyl]sulfanyl}-8-oxo-2H,7H,8H-[1,3]dioxolo[4,5-g]quinazolin-7-yl)-N-[(4-methoxyphenyl)methyl]hexanamide
  • 6-(6-{[(4-fluorophenyl)methyl]sulfanyl}-8-oxo-2H,7H,8H-[1,3]dioxolo[4,5-g]quinazolin-7-yl)-N-[(4-methoxyphenyl)methyl]hexanamide
  • 6-(6-{[(2-chlorophenyl)methyl]sulfanyl}-8-oxo-2H,7H,8H-[1,3]dioxolo[4,5-g]quinazolin-7-yl)-N-[(4-methoxyphenyl)methyl]hexanamide
  • 6-(6-{[(3-chlorophenyl)methyl]sulfanyl}-8-oxo-2H,7H,8H-[1,3]dioxolo[4,5-g]quinazolin-7-yl)-N-[(4-methoxyphenyl)methyl]hexanamide
  • 6-(6-{[(4-chlorophenyl)methyl]sulfanyl}-8-oxo-2H,7H,8H-[1,3]dioxolo[4,5-g]quinazolin-7-yl)-N-[(4-methoxyphenyl)methyl]hexanamide
  • N-(4-methoxybenzyl)-6-[6-[(3-nitrobenzyl)thio]-8-oxo[1,3]dioxolo[4,5-g]quinazolin-7(8H)-yl]hexanamide