O-Desmethyl Metoprolol

Suppliers

Names

[ CAS No. ]:
62572-94-5

[ Name ]:
O-Desmethyl Metoprolol

[Synonym ]:
1-[4-(2-hydroxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol

Chemical & Physical Properties

[ Density]:
1.085g/cm3

[ Boiling Point ]:
424.6ºC at 760 mmHg

[ Melting Point ]:
70-72ºC

[ Molecular Formula ]:
C14H23NO3

[ Molecular Weight ]:
253.33700

[ Flash Point ]:
210.6ºC

[ Exact Mass ]:
253.16800

[ PSA ]:
61.72000

[ LogP ]:
1.35000

[ Index of Refraction ]:
1.531

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DA0512150
CHEMICAL NAME :
Benzeneethanol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-
CAS REGISTRY NUMBER :
62572-94-5
LAST UPDATED :
198809
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H23-N-O3
MOLECULAR WEIGHT :
253.38

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PBPSDY Pharmacological and Biochemical Properties of Drug Substances. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.1- 1977- Volume(issue)/page/year: 2,186,1979

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
DA0512150

Articles

Identification of transformation products from β-blocking agents formed in wetland microcosms using LC-Q-ToF.

J. Mass Spectrom. 51 , 207-18, (2016)

Identification of degradation products from trace organic compounds, which may retain the biological activity of the parent compound, is an important step in understanding the long-term effects of the...


More Articles

Related Compounds

  • O-desmethyl Mebeverine acid
  • (4R)-4-(ethylamino)-2-(3-hydroxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide-1,1-dioxide
  • O-Desmethyl Midostaurin
  • O-Desmethyl apixaban
  • O-Desmethyl Felodipine
  • O-Desmethyl Mycophenolate Mofetil
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • Methyl 2-acetamido-3-(6-bromopyridin-3-yl)propanoate
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • Tert-butyl (2S)-2-(methylcarbamoyl)aziridine-1-carboxylate
  • tert-Butyl-DL-alanine