2,4-Dihydroxypyridine

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Names

[ CAS No. ]:
626-03-9

[ Name ]:
2,4-Dihydroxypyridine

[Synonym ]:
2,4-Dihydoxypyridine
3-DEAZAURACIL
4-Hydroxy-2(1H)-pyridinone
4-Hydroxypyridin-2(1H)-on
EINECS 210-924-8
4,6-Pyridinediol
2,4-Dihydroxy pyridine
2,4-Pyridinediol
4-hydroxypyridin-2(1H)-one
2,4-dihydroxy-pyridine
2(1H)-Pyridinone, 4-hydroxy-
pyridine-2,4-diol
MFCD00006273
2,4-Pridinediol
4-Hydroxy-2(1H)-pyridinon
4-Hydroxy-2-pyridone
4-diol
Pyridin-2,4-diol

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
509.8±30.0 °C at 760 mmHg

[ Melting Point ]:
272-276 °C(lit.)

[ Molecular Formula ]:
C5H5NO2

[ Molecular Weight ]:
111.099

[ Flash Point ]:
262.1±24.6 °C

[ Exact Mass ]:
111.032028

[ PSA ]:
53.35000

[ LogP ]:
-2.65

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.625

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UV1146800
CHEMICAL NAME :
2(1H)-Pyridone, 4-hydroxy-
CAS REGISTRY NUMBER :
626-03-9
LAST UPDATED :
199206
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C5-H5-N-O2
MOLECULAR WEIGHT :
111.11
WISWESSER LINE NOTATION :
T6NJ BQ DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4895 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 23,815,1985

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
UV1146800

[ HS Code ]:
2933399090

Precursor & DownStream

Precursor

  • 2,4-Dimethoxypyridine
  • 4-Hydroxypyridine
  • 3-Cyano-1,2-dihydro-4-hydroxy-2-oxopyridine
  • 6-chloro-2-hydroxy-4-oxo-1H-pyridine-3-carbonitrile

DownStream

  • 4-Hydrazinylpyridin-2(1H)-one
  • 4-Amino-2-hydroxypyridine
  • 2,4-Dibromopyridine
  • 2,3,4-Tribromopyridine
  • 4-chloro-3-nitro-2-phenylmethoxypyridine
  • 4-(2,4-dichlorophenyl)-3-nitro-2-phenylmethoxypyridine
  • 4-[(4-chlorophenyl)methoxy]-1H-pyridin-2-one
  • 2,4-Dichloro-3-iodopyridine
  • 3-Nitro-2,4-pyridinediamine
  • 2,3,5-Trichloropyridin-4-amine

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis of diazaphenoxathiin nucleosides from 3-deazauridine and their chemical properties.

Nucleic Acids Symp. Ser. (12) , 13-6, (1983)

New method for a synthesis of diazaphenoxathiin skeleton from 3-deazauracil derivatives is reported. It became possible to convert 3-deazauridine to 3-deazacytidine via an excellent intermediate "diaz...

Structure-activity relationship of ligands of dihydrouracil dehydrogenase from mouse liver.

Biochem. Pharmacol. 38(9) , 1471-80, (1989)

One hundred and five nucleobase analogues were screened as inhibitors of dihydrouracil dehydrogenase (DHUDase, EC 1.3.1.2) from mouse liver. 5-Benzyloxybenzyluracil, 1-deazauracil (2,6-pyridinediol), ...

[Presynaptic effects of aminopyridines on the neuromuscular junction of vertebrates].

J. Pharmacol. 16 Suppl 2 , 109-44, (1985)

In this review the effects of aminopyridines and chemically related compounds are documented in an attempt to analyse the mechanism underlying their presynaptic actions at the vertebrate neuromuscular...


More Articles

Related Compounds

  • 2,4-Dihydroxypyridine
  • 2,4-dihydroxypyridine-1-oxide
  • 3,5-dibromo-2,4-dihydroxypyridine
  • 2,4-dinitrophenyl-dioleoylphosphatidylethanolamine
  • 2,4-Quinazolinediamine, 7-[2-(4-chlorophenyl)-1-pyrrolidinyl]-
  • [2-(4,4-dimethyl-3-oxopentyl)-1-hydroxycyclopentyl]-hydroxy-oxophosphanium
  • Ethyl 1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate
  • N-[(6-bromopyridin-3-yl)sulfonyl]-3-(4-oxo-3,4-dihydro-1,2,3-benzotriazin-3-yl)propanamide
  • 1-(Tetrahydrofuran-2-yl)prop-2-en-1-amine
  • N-[(6-bromopyridin-3-yl)sulfonyl]-3-methanesulfonyl-4-methylbenzamide
  • 3-(2-Methylphenyl)-1,2,4-oxadiazole-5-thiol
  • 2-[(1-Hydroxypropan-2-yl)sulfanyl]-1-(2-methylphenyl)ethan-1-one
  • 1-Iodo-4-(3,3,3-trifluoropropoxy)benzene
  • 1-(4-Bromophenyl)-2-[(1-hydroxypropan-2-yl)sulfanyl]ethan-1-one
  • 2-(5-Bromo-2-pyridinyl)-1H-benzimidazole
  • 2-[(1-Hydroxypropan-2-yl)sulfanyl]-1-(4-iodophenyl)ethan-1-one
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