1-Methylpiperidine

Names

[ CAS No. ]:
626-67-5

[ Name ]:
1-Methylpiperidine

[Synonym ]:
1-methylpiperidine
MFCD00006491
EINECS 210-959-9
N-METHYL PIPERIDINE

Chemical & Physical Properties

[ Density]:
0.817 g/mL at 20 °C(lit.)

[ Boiling Point ]:
106-107 °C(lit.)

[ Melting Point ]:
-50 °C

[ Molecular Formula ]:
C₆H₁₃N

[ Molecular Weight ]:
99.17410

[ Flash Point ]:
38 °F

[ Exact Mass ]:
99.10480

[ PSA ]:
3.24000

[ LogP ]:
1.04000

[ Index of Refraction ]:
n20/D 1.438

[ Water Solubility ]:
miscible

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TN1225000

CHEMICAL NAME :: Piperidine, 1-methyl-

CAS REGISTRY NUMBER :: 626-67-5

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C6-H13-N

MOLECULAR WEIGHT :: 99.20

WISWESSER LINE NOTATION :: T6NTJ A1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 86,1325,1978

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BDCGAS Berichte der Deutschen Chemischen Gesellschaft. (Leipzig, Ger. Dem. Rep.) V.1-61, 1868-1928. For publisher information, see CHBEAM. Volume(issue)/page/year: 34,2408,1901

Safety Information

[ Symbol ]:

GHS02, GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H314

[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable;C:Corrosive;

[ Risk Phrases ]:
R11;R20/22;R34

[ Safety Phrases ]:
S7-S16-S26-S36/37/39-S45-S9-S33

[ RIDADR ]:
UN 3286 3/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
TN1225000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
29333999

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

1-methyl-5,6-dihydro-2H-pyridine
carbon monoxide
Methanol
5-Aminopentanol
Formylpiperidine
1,5-Pentanediol
2-Piperidinone,1-methyl-
Piperidine
methyl iodide
Methionine,1-methylethyl ester, hydrochloride (9CI)

DownStream

1-(chloromethyl)-1-methylpiperidin-1-ium,chloride
Bromobenzene
1-Phenylpiperidine
benzene
Biphenyl
Carbon dioxide
Ethyl benzoate
Benzoic anhydride
1-Butyl-1-methylpiperidinium bromide
PIPERIDINE, 1-CHLORO-

Customs

[ HS Code ]: 29333999

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