Isoquinoline,3,4-dihydro-6,7-dimethoxy-1-methyl-, hydrochloride (1:1)

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Names

[ CAS No. ]:
6268-86-6

[ Name ]:
Isoquinoline,3,4-dihydro-6,7-dimethoxy-1-methyl-, hydrochloride (1:1)

[Synonym ]:
6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline hydrochloride
1-methyl-6,7-dimethoxy-3,4-dihydroisoquinoline hydrochloride
3,4-dihydro-6,7-dimethoxy-1-methylisoquinoline hydrochloride
dimethoxy-6,7 methyl-1 dihydro-3,4 isoquinoleine chlorhydrate
6,7-Dimethoxy-1-methyl-3,4-dihydro-isochinolin,Hydrochlorid

Chemical & Physical Properties

[ Boiling Point ]:
312.1ºC at 760 mmHg

[ Molecular Formula ]:
C12H16ClNO2

[ Molecular Weight ]:
241.71400

[ Flash Point ]:
117ºC

[ Exact Mass ]:
241.08700

[ PSA ]:
30.82000

[ LogP ]:
2.30650

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NW7628860
CHEMICAL NAME :
Isoquinoline, 3,4-dihydro-6,7-dimethoxy-1-methyl-, hydrochloride
CAS REGISTRY NUMBER :
6268-86-6
LAST UPDATED :
198806
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H15-N-O2.Cl-H
MOLECULAR WEIGHT :
241.74

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
108 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 76,263,1942

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Acetamide, N-(3,4-dimethoxyphenethyl)- (8CI)
  • phosphoryl trichloride
  • 3,4-Dimethoxyphenethylamine

DownStream

  • 6,7-Dimethoxy-1-methyl-3,4-dihydroisoquinoline

Related Compounds

  • 2-(trichloromethyl)-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine
  • 1-[2-(trichloromethyl)-1H-imidazol-4-yl]ethan-1-amine
  • 6-Cyclopropyl-2-(trichloromethyl)pyrimidin-4-amine
  • 6-Propyl-2-(trichloromethyl)pyrimidin-4-amine
  • ethyl({[2-(trichloromethyl)-1H-imidazol-4-yl]methyl})amine
  • 5-[(Methylamino)methyl]-2-(trichloromethyl)-3,4-dihydropyrimidin-4-one
  • 4-Cyclopropyl-2-(trichloromethyl)pyrimidin-5-amine
  • ethyl 5-(2-methylbutyl)-1H-1,2,3-triazole-4-carboxylate
  • 2,5-Dimethyl-4-(pyridin-4-yl)benzaldehyde
  • ethyl 5-(1H-pyrazol-4-yl)-1H-1,2,3-triazole-4-carboxylate
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