Propargyl acetate

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Names

[ CAS No. ]:
627-09-8

[ Name ]:
Propargyl acetate

[Synonym ]:
prop-2-ynyl acetate
MFCD00041601

Chemical & Physical Properties

[ Density]:
0.989

[ Boiling Point ]:
27-28ºC(lit.)

[ Molecular Formula ]:
C5H6O2

[ Molecular Weight ]:
98.09990

[ Flash Point ]:
91 °F

[ Exact Mass ]:
98.03680

[ PSA ]:
26.30000

[ LogP ]:
0.18270

[ Appearance of Characters ]:
Liquid | Clear colorless

[ Index of Refraction ]:
n20/D 1.417(lit.)

[ Storage condition ]:
Flammables area

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UK5076000
CHEMICAL NAME :
2-Propyn-1-ol, acetate
CAS REGISTRY NUMBER :
627-09-8
BEILSTEIN REFERENCE NO. :
1742046
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C5-H6-O2
MOLECULAR WEIGHT :
98.11

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 28(6),55,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
520 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 28(6),55,1984

Safety Information

[ Symbol ]:

GHS02, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H301-H312-H332

[ Precautionary Statements ]:
P280-P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R10;R20/21/22

[ Safety Phrases ]:
S23-S36/37

[ RIDADR ]:
UN 1992 3/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
UK5076000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(3)

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Propargyl alcohol
  • Acetyl chloride
  • acetic acid
  • Ethanoic anhydride
  • 2-(propargyloxy)tetrahydropyran
  • ethyl acetate
  • 1-Propyne,3-(methoxymethoxy)-
  • prop-2-ynyl 2-bromoacetate
  • Propyne
  • Sodium acetate

DownStream

  • 2,6-DIPHENYLPYRIDINE
  • Allene
  • 6-(4-methyl-3H-1,3-oxazol-2-ylidene)cyclohexa-2,4-dien-1-one
  • resmethrin
  • Acetoxyacetic acid
  • 4-morpholin-4-ylbut-2-ynyl acetate
  • ETHANONE, 1-(2,4-DIMETHYL-3-FURANYL)-

Articles

Asymmetric synthesis of ?-hydroxy a, ß-unsaturated aldehydes via enantioselective direct addition of propargyl acetate to aldehydes El-Sayed E, et al.

Org. Lett. 3.19 , 3017-3020, (2001)

Nucleophilic reactions of propargyl acetates mediated by titanocene dichloride and magnesium Yang F, et al.

Tetrahedron Lett. 42.15 , 2839-2841, (2001)

Investigations on the ion transport mechanism in conducting polymer films Casalbore-Miceli G, et al.

Solid State Ionics 131.3 , 311-321, (2000)


More Articles

Related Compounds

  • Propargyl a-D-mannopyranoside
  • Propargyl-PEG4-CH2CH2-Boc
  • Propargyl-PEG2-amine
  • propargyl m-nitrobenzenesulphonate
  • Propargyl-PEG3-Boc
  • Propargyl benzenesulfonate
  • 3-({Bicyclo[3.1.0]hexan-1-yl}amino)-2,2-difluoropropanoic acid
  • (3-Amino-2,2-difluoropropyl)(but-3-yn-1-yl)methylamine
  • 3-[(Cyclopropylmethyl)(ethyl)amino]-2,2-difluoropropanoic acid
  • 2,2-Difluoro-3-[(2-propylcyclopropyl)amino]propanoic acid
  • 2,2-Difluoro-3-[(1-methylpyrrolidin-3-yl)amino]propanoic acid
  • 3-(4-Ethenylpiperidin-1-yl)-2,2-difluoropropan-1-amine
  • [2,2-Difluoro-3-(oxetan-3-yloxy)propyl](ethyl)amine
  • {2,2-Difluoro-3-[(3-methylbut-3-en-1-yl)oxy]propyl}(ethyl)amine
  • Ethyl 3-[cyclopropyl(methyl)amino]-2,2-difluoropropanoate
  • N-({6-azaspiro[3.4]octan-8-yl}methyl)cyclobutanamine
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