APM

Suppliers

Names

[ CAS No. ]:
627-76-9

[ Name ]:
APM

[Synonym ]:
2-Aminopimelate
Heptanedioic acid, 2-amino-, (±)-
UNII:V76629V970
DL-2-Aminopimelate
DL-2-Aminopimelic Acid
Heptanedioic acid, 2-amino-
2-Aminoheptanedioic acid
dl-α-Aminopimelic acid
EINECS 211-011-7
(±)-2-Aminopimelic acid
APM
MFCD00053314

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
378.5±37.0 °C at 760 mmHg

[ Melting Point ]:
223 °C (dec.)(lit.)

[ Molecular Formula ]:
C7H13NO4

[ Molecular Weight ]:
175.182

[ Flash Point ]:
182.7±26.5 °C

[ Exact Mass ]:
175.084457

[ PSA ]:
100.62000

[ LogP ]:
-0.66

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.510

[ Storage condition ]:
Store at RT.

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Precursor & DownStream

Precursor

  • 2-KETOPIMELIC ACID
  • Ethyl 2-oxocyclohexanecarboxylate
  • 7,7-dichloro-hept-6-enoic acid
  • DL-Norleucine, 6-hydroxy-
  • (D,L)-Cbz-ε-hydroxynorleucine
  • 1,4-Dibromobutane
  • Ethyl phthalimidomalonate
  • 1-acetylamino-5-cyano-pentane-1,1,5-tricarboxylic acid triethyl ester

DownStream

  • DL-Lysine

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Peptides containing 2-aminopimelic acid. Synthesis and study of in vitro effects on bacterial cells.

Int. J. Pept. Protein Res. 37 , 103-111, (1991)

Taking advantage of the peptide transport strategy, we have designed and synthesized several new peptides containing 2-aminopimelic acid (Apm), an inhibitor of the diaminopimelate pathway in bacteria:...

Peptides of 2-aminopimelic acid: antibacterial agents that inhibit diaminopimelic acid biosynthesis.

J. Med. Chem. 29 , 89-95, (1986)

Succinyl-CoA:tetrahydrodipicolinate-N-succinyltransferase is a key enzyme in the biosynthesis of diaminopimelic acid (DAP), a component of the cell wall peptidoglycan of nearly all bacteria. This enzy...

N-methylnicotinamide and nicotinamide N-methyltransferase are associated with microRNA-1291-altered pancreatic carcinoma cell metabolome and suppressed tumorigenesis.

Carcinogenesis 35(10) , 2264-72, (2014)

Platinum resistance is the most crucial problem for treatment of ovarian cancer. There is a clinical need for new treatment strategies which overcome platinum resistance. Recently high level of AKT wa...


More Articles


Related Compounds

  • APM
  • BAPTA-APM
  • APM-morpholidate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine