1-Fluorenecarboxylic Acid

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Names

[ CAS No. ]:
6276-03-5

[ Name ]:
1-Fluorenecarboxylic Acid

[Synonym ]:
MFCD00001130
EINECS 228-472-5
1-Fluorenecarboxylic Acid
9H-Fluorene-1-carboxylic acid

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
413.3±24.0 °C at 760 mmHg

[ Melting Point ]:
246-248 °C(lit.)

[ Molecular Formula ]:
C14H10O2

[ Molecular Weight ]:
210.228

[ Flash Point ]:
185.4±17.6 °C

[ Exact Mass ]:
210.068085

[ PSA ]:
37.30000

[ LogP ]:
3.84

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.679

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916399090

Synthetic Route

Precursor & DownStream

Precursor

  • 9-Oxo-9H-fluorene-1-carboxylic acid
  • 9H FLUORENE
  • Carbon dioxide
  • Fluoranthene
  • Water
  • Aluminium chloride
  • benzene
  • Trichloroacetic acid

DownStream

  • 1-Methyl-9H-fluorene
  • 9H FLUORENE
  • Carbon dioxide
  • Acetamide,N-9H-fluoren-1-yl-
  • 9H-Fluorene, 1-methoxy-
  • methyl 9H-fluorene-1-carboxylate
  • 9H-fluoren-1-amine
  • 9H-Fluoren-1-ol
  • 9-Oxo-9H-fluorene-1-carboxylic acid
  • 9-bromo-9H-fluorene-1-carboxylic acid

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Fluorene-1-carboxylic acid.

Acta Crystallogr. C 52 ( Pt 4) , 907-10, (1996)

In fluorene-1-carboxylic acid, C14H10O2, the sole hydrogen bond is of the cyclic dimer type about a center of symmetry. The carboxyl H atom is ordered. Distances in the fluorene core are very similar ...

Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 9-oxo-9H-fluorene ring.

Bioorg. Med. Chem. Lett. 20(3) , 1288-92, (2010)

As a continuation of our studies of apoptosis inducing 9-oxo-9H-fluorene-1-carboxamides as potential anticancer agents, we explored modification of the 9-oxo-9H-fluorene ring. SAR studies showed that ...


More Articles


Related Compounds

  • 9-Oxo-1-fluorenecarboxylic acid
  • 9-HYDROXY-1-FLUORENECARBOXYLIC ACID)
  • butyl 9-(dicyanomethylidene)fluorene-1-carboxylate
  • methyl 2,7-dinitro-9-oxofluorene-1-carboxylate
  • Flurecol
  • 2-(1-methylpyrrolidin-2-yl)ethyl 9H-fluorene-9-carboxylate