Benzenemethanamine,N,2-dimethyl-N-nitroso-

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Names

[ CAS No. ]:
62783-48-6

[ Name ]:
Benzenemethanamine,N,2-dimethyl-N-nitroso-

[Synonym ]:
Benzylamine,o-dimethyl-N-nitroso
BENZYLAMINE,N,o-DIMETHYL-N-NITROSO

Chemical & Physical Properties

[ Density]:
1.02g/cm3

[ Boiling Point ]:
316.7ºC at 760 mmHg

[ Molecular Formula ]:
C9H12N2O

[ Molecular Weight ]:
164.20400

[ Flash Point ]:
145.3ºC

[ Exact Mass ]:
164.09500

[ PSA ]:
32.67000

[ LogP ]:
2.10820

[ Index of Refraction ]:
1.524

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DP4760000
CHEMICAL NAME :
Benzylamine, N,o-dimethyl-N-nitroso-
CAS REGISTRY NUMBER :
62783-48-6
LAST UPDATED :
199203
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C9-H12-N2-O
MOLECULAR WEIGHT :
164.23
WISWESSER LINE NOTATION :
ONN1&1R B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
90 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - chromodacryorrhea Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie. (Berlin, Fed. Rep. Ger.) V.76-92, 1971-78. For publisher information, see JCROD7. Volume(issue)/page/year: 88,231,1977 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
300 mg/kg/29W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
REFERENCE :
ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie. (Berlin, Fed. Rep. Ger.) V.76-92, 1971-78. For publisher information, see JCROD7. Volume(issue)/page/year: 88,231,1977
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
31640 mg/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
REFERENCE :
JCROD7 Journal of Cancer Research and Clinical Oncology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.93- 1979- Volume(issue)/page/year: 95,123,1979

Related Compounds

  • 1H-Benzimidazol-1-amine,N,2-dimethyl-N-nitroso-(9CI)
  • 2-methyl-2-[methyl(nitroso)amino]propanoic acid
  • N,2-Dimethyl-N-nitroso-1-propanamine
  • Propanamide,N,2-dimethyl-
  • Benzenamine,N,2-dimethyl-
  • N-(2-chloroethyl)-2,6-dimethyl-N-nitroso-morpholine-4-carboxamide
  • 5-cyclopropyl-N-(isoxazol-4-yl)isoxazole-3-carboxamide
  • N-(isoxazol-4-yl)-4-(trifluoromethoxy)benzamide
  • Ethyl 5-(2-(4-chlorophenoxy)-2-methylpropanamido)pyrazolo[1,5-a]pyridine-3-carboxylate
  • Ethyl 5-(5-phenylisoxazole-3-carboxamido)pyrazolo[1,5-a]pyridine-3-carboxylate
  • ethyl 5-(2-(2-oxobenzo[d]oxazol-3(2H)-yl)acetamido)pyrazolo[1,5-a]pyridine-3-carboxylate
  • Ethyl 5-(4-(trifluoromethoxy)benzamido)pyrazolo[1,5-a]pyridine-3-carboxylate
  • Benzo[d]thiazol-6-yl(4-(pyrazolo[1,5-a]pyridine-3-carbonyl)piperazin-1-yl)methanone
  • 2-Phenoxy-1-(4-(pyrazolo[1,5-a]pyridine-3-carbonyl)piperazin-1-yl)propan-1-one
  • 2-(2-Chlorophenyl)-1-(4-(pyrazolo[1,5-a]pyridine-3-carbonyl)piperazin-1-yl)ethanone
  • (6-methoxy-1H-indol-2-yl)(4-(pyrazolo[1,5-a]pyridine-3-carbonyl)piperazin-1-yl)methanone
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