n-Hexanamide

Names

[ CAS No. ]:
628-02-4

[ Name ]:
n-Hexanamide

[Synonym ]:
n-Caproamide
Hexanoamide
hexanoic acid amide
Hexanamide
4-02-00-00929 (Beilstein Handbook Reference)
Capronamide
EINECS 211-024-8
Hexylamide
n-Hexanamide
Alkamid
hexaneamide
Hexamide
MFCD00008046
caproamide
n-hexylamide

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
255.0±0.0 °C at 760 mmHg

[ Melting Point ]:
100-102 °C(lit.)

[ Molecular Formula ]:
C₆H₁₃NO

[ Molecular Weight ]:
115.174

[ Flash Point ]:
102.2±18.4 °C

[ Exact Mass ]:
115.099716

[ PSA ]:
43.09000

[ LogP ]:
0.89

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.434

[ Stability ]:
Stable. Combustible. Incompatible with acids, bases, strong oxidizing agents.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MN7875000

CHEMICAL NAME :: Hexanamide

CAS REGISTRY NUMBER :: 628-02-4

BEILSTEIN REFERENCE NO. :: 1741923

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C6-H13-N-O

MOLECULAR WEIGHT :: 115.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 438 gm/kg/1Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Blood - tumors Blood - lymphoma, including Hodgkin's disease

REFERENCE :: JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 3(5-6),149,1980

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
MN7875000

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

N-acetylhexanamide
Pentyl isocyanate
Amylamine hydrochloride
capronitrile
Amyl ketone
Acetamide
1-Hexanoic acid
1-Hexanol
Hexanal
N-caproylglycine

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Zirconium-mediated conversion of amides to nitriles: a surprising additive effect.

Angew. Chem. Int. Ed. Engl. 43(40) , 5375-7, (2004)

Aliphatic and enantioselective amidases: from hydrolysis to acyl transfer activity.

J. Appl. Microbiol. 91(3) , 381-93, (2001)

Carcinogenesis bioassay of acetamide, hexanamide, adipamide, urea and P-tolylurea in mice and rats.

J. Environ. Pathol. Toxicol. 3(5-6) , 149-70, (1980)

As a part of the National Cancer Institute's effort to screen environmental and occupational chemicals for chronic toxicity and carcinogenicity, the amides acetamide, hexanamide, adipamide, urea, and ...