GLUTACONIC ACID

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Names

[ CAS No. ]:
628-48-8

[ Name ]:
GLUTACONIC ACID

[Synonym ]:
Glutaconic Acid
(E)-pent-2-enedioic acid
MFCD00002784

Chemical & Physical Properties

[ Melting Point ]:
137-139ºC(lit.)

[ Molecular Formula ]:
C5H6O4

[ Molecular Weight ]:
130.09900

[ Exact Mass ]:
130.02700

[ PSA ]:
74.60000

[ LogP ]:
0.10190

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • dimethyl pent-2-enedioate
  • 2,3-dibromo-glutaric acid
  • Propiolic acidd
  • Diethyl 3-hydroxypentanedioate
  • Glutaconsaeure-diethylester
  • 6-Chloropyridn-2-ol
  • (E)-2-Pentenedioic acid diethyl ester
  • diethyl 2-bromopentanedioate
  • Glutaric acid
  • trans-Glutaconic acid

DownStream

  • 2H-Pyran-2-one,6-(1-pentyn-1-yl)-
  • 3-Hydroxyglutaric acid
  • trans-Glutaconic acid
  • 6-chloropyran-2-one
  • 6-Pentyl-2H-pyran-2-one
  • 1-Thio-4-chromanone-2-acetic acid
  • 2-[4-(2,6-dimethoxyphenoxy)butoxy]-1,3-dimethoxybenzene
  • 2H-Pyran-2,6(3H)-dione

Articles

Effects of structural analogues of the substrate and allosteric regulator of the human mitochondrial NAD(P)+-dependent malic enzyme.

Bioorg. Med. Chem. 17 , 5414-9, (2009)

Fumarate, a four-carbon trans dicarboxylic acid, is the allosteric activator of the human mitochondrial NAD(P)(+)-dependent malic enzyme (m-NAD(P)-ME). In this paper, we discuss the effects of the str...

Induction of the mitochondrial permeability transition in vitro by short-chain carboxylic acids.

Biochem. Biophys. Res. Commun. 272(2) , 431-5, (2000)

We recently reported that acrylic acid (AA) induces the MPT in vitro, which we suggested might be a critical event in the acute inflammatory and hyperplastic response of the olfactory epithelium. The ...

Efficient synthesis and neuroprotective effect of substituted 1,3-diphenyl-2-propen-1-ones.

J. Med. Chem. 51 , 4054-8, (2008)

An efficient synthesis involving a key aldol reaction and biological properties of 1,3-diphenyl-2-propen-1-ones 8- 20 is described. The in vitro activity for 2,2-diphenyl-1-picrylhydrazyl (DPPH) radic...


More Articles

Related Compounds

  • Glutaconic acid
  • cis-glutaconic acid
  • Glutaconic acid diethyl
  • Glutaconic acid diethyl
  • Glutaconic acid dimethyl ester
  • cis-glutaconic acid diethyl ester
  • 1-(4-{[(6-Methylpyrimidin-4-yl)oxy]methyl}piperidin-1-yl)ethan-1-one
  • 1-(1,2,3,6-tetrahydropyridin-1-yl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-one
  • 4-{[1-(4,4-Difluorocyclohexanecarbonyl)piperidin-4-yl]methoxy}-2-methylpyridine
  • 4-(1,2,3,6-Tetrahydropyridine-1-carbonyl)pyridine
  • 3-(1,2,3,6-Tetrahydropyridine-1-carbonyl)pyridine
  • 1-Methyl-4-[[4-[[6-(trifluoromethyl)pyridin-2-yl]oxymethyl]piperidin-1-yl]methyl]pyrrolidin-2-one
  • 4-{[4-(1H-pyrazol-1-yl)piperidin-1-yl]methyl}pyridine
  • 7-[2-(Tert-butoxycarbonylamino)acetyl]amino-2,3-dihydro-1h-imidazo[1,2-b]pyrazole
  • 4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrimidin-3-amine sulfate
  • 4-{[1-(Cyclohex-3-ene-1-carbonyl)piperidin-4-yl]methoxy}-2-methylpyridine
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