p-aminophenylmercuric acetate

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Names

[ CAS No. ]:
6283-24-5

[ Name ]:
p-aminophenylmercuric acetate

[Synonym ]:
p-Aminophenylmercuriacetate
P-aminophenylmercuric acetate
EINECS 228-497-1
4-Aminophenylmercuriacetate
4-amino-phenylmercury (1+),acetate
p-aminophenylmercury acetate
4-Amino-phenylquecksilber(1+),Acetat
4-Aminophenylmercuric acetate
(Acetato-O)(4-aminophenyl)mercury
MFCD00007820
p-(Acetoxymercuri)aniline
(Acetato)(p-aminophenyl)mercury
4-(Acetoxymercurio)aniline
p-NH2C6H4HgCH3CO2
APMA

Chemical & Physical Properties

[ Melting Point ]:
163-165 °C(lit.)

[ Molecular Formula ]:
C8H9HgNO2

[ Molecular Weight ]:
351.75

[ Exact Mass ]:
353.03400

[ PSA ]:
52.32000

[ LogP ]:
1.03590

[ Water Solubility ]:
DMSO: 10 mg/mL, soluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OV5550000
CHEMICAL NAME :
Mercury, (acetato)(p-aminophenyl)-
CAS REGISTRY NUMBER :
6283-24-5
BEILSTEIN REFERENCE NO. :
3664749
LAST UPDATED :
199712
DATA ITEMS CITED :
23
MOLECULAR FORMULA :
C8-H9-Hg-N-O2
MOLECULAR WEIGHT :
351.77
WISWESSER LINE NOTATION :
ZR D-HG-OV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
13 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 31,87,1927
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
18 mg/kg
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04750 *** REVIEWS *** ACGIH TLV-TWA 0.1 mg(Hg)/m3 (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.05 mg(Hg)/m3 DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8. Volume(issue)/page/year: 3,22,1973 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.05 mg(Hg)/m3;Skin JAN 1993 OEL-BELGIUM:TWA 0.05 mg(Hg)/m3;Skin JAN 1993 OEL-DENMARK:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-FINLAND:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-FRANCE:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-GERMANY:TWA 0.01 ppm (0.1 mg(Hg)/m3) JAN 1993 OEL-HUNGARY:TWA 0.02 mg(Hg)/m3;STEL 0.04 mg(Hg)/m3 JAN 1993 OEL-JAPAN:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.05 mg(Hg)/m3;STEL 0.15 mg(Hg)/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-POLAND:TWA 0.01 mg(Hg)/m3 JAN 1993 OEL-RUSSIA:TWA 0.05 mg(Hg)/m3;STEL 0.01 mg(Hg)/m3 JAN 1993 OEL-SWEDEN:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-THAILAND:STEL 0.05 mg(Hg)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.05 mg(Hg)/m3;STEL 0.15 mg(Hg)/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO MERCURY, ARYL AND INORGANIC-air:CL 0.1 mg/m3 (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992

Safety Information

[ Hazard Codes ]:
T+,N

[ Risk Phrases ]:
R26/27/28;R33;R50/53

[ Safety Phrases ]:
S13-S28-S36-S45-S60-S61

[ RIDADR ]:
UN 2025 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
OV5550000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(a)

Synthetic Route

Precursor & DownStream

Precursor

  • mercuric acetate

DownStream

  • 4-Iodoaniline
  • 4-(4-aminophenyl)aniline
  • 4,4'-Diaminobenzophenone
  • N-(4-iodophenyl)-1-methylpyridin-1-ium-3-carboxamide,iodide
  • N-(4-iodophenyl)-1-methyl-4H-pyridine-3-carboxamide

Related Compounds

  • Substance P acetate salt
  • substance p acetate salt hydrate, biochemika
  • (D-Pro2,D-Trp7·9)-Substance P acetate salt
  • p-Chlorobenzyl acetate
  • p-ethylbenzyl acetate
  • p-mercaptophenyl acetate
  • 5-(2-Isocyanatopropan-2-yl)-2-(pyrrolidin-1-yl)pyridine
  • rac-3-{[(1R,5S)-bicyclo[3.1.0]hexan-2-yl]carbamoyl}-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanamido]-2-(1-methyl-1H-pyrazol-5-yl)acetic acid
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde