6-(Trifluoromethyl)-4,5-dihydropyridazin-3(2H)-one

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Names

[ CAS No. ]:
628332-15-0

[ Name ]:
6-(Trifluoromethyl)-4,5-dihydropyridazin-3(2H)-one

[Synonym ]:
3-(trifluoromethyl)-4,5-dihydro-1H-pyridazin-6-one

Chemical & Physical Properties

[ Density]:
1.57±0.1 g/cm3(Predicted)

[ Melting Point ]:
75-77 °C

[ Molecular Formula ]:
C5H5F3N2O

[ Molecular Weight ]:
166.10100

[ Exact Mass ]:
166.03500

[ PSA ]:
44.95000

[ LogP ]:
0.52620

[ Storage condition ]:
2-8℃

Synthetic Route

Precursor & DownStream

Precursor

  • Ethyl trifluoroacetate
  • Diethyl succinate
  • tert-butyl 3-[5-oxo-4-(propan-2-yl)-2-(trifluoromethyl)-2,5-dihydro-1,3-oxazol-2-yl]propanoate

DownStream

  • 6-(Trifluoromethyl)pyridazin-3(2H)-one

Related Compounds

  • 2-(4-FLUOROPHENYL)-6-(TRIFLUOROMETHYL)-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE
  • 2-(4-METHOXYPHENYL)-6-(TRIFLUOROMETHYL)-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE
  • 6-(4-bromophenyl)-4-(trifluoromethyl)-4,5-dihydropyridazin-3(2H)-one
  • 2-phenyl-6-(trifluoromethyl)-4,5-dihydropyridazin-3-one
  • 6-methyl-5-(3-(trifluoromethyl)benzylidene)-4,5-dihydropyridazin-3(2H)-one
  • 6-(2-bromophenyl)-4,5-dihydropyridazin-3(2H)-one
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • methyl 4-(4-bromo-3-methylphenyl)-4H-1,4-benzothiazine-2-carboxylate 1,1-dioxide
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 1-[2-Hydroxy-4-(4-iodo-benzyloxy)-3-propyl-phenyl]-ethanone
  • tert-Butyl-DL-alanine