9-Fluorene acetic acid

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Names

[ CAS No. ]:
6284-80-6

[ Name ]:
9-Fluorene acetic acid

[Synonym ]:
9H-Fluoren-9-ylacetic acid
MFCD00013262
9H-Fluorene-9-acetic acid
2-(9H-fluoren-9-yl)acetic acid
9-Fluorene acetic acid

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
436.9±14.0 °C at 760 mmHg

[ Melting Point ]:
133-135 °C(lit.)

[ Molecular Formula ]:
C15H12O2

[ Molecular Weight ]:
224.255

[ Flash Point ]:
333.6±15.2 °C

[ Exact Mass ]:
224.083725

[ PSA ]:
37.30000

[ LogP ]:
3.38

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.636

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916399090

Synthetic Route

Precursor & DownStream

Precursor

  • (1-cyanospiro[cyclopropane-2,9'-fluorene]-1-yl) acetate
  • ethyl 2-(9H-fluoren-9-yl)acetate
  • 9-Fluorenone
  • Acetic acid,2-(9H-fluoren-9-ylidene)-, ethyl ester
  • Acetic acid,9H-fluoren-9-ylidene-
  • 9-fluorenol
  • sodium 1,3-diethoxy-1,3-dioxopropan-2-ide
  • 9-bromofluorene
  • 2-Phenylbenzaldehyde
  • 2-trimethylsilyloxyprop-2-enenitrile

DownStream

  • 9H FLUORENE
  • 9-methylfluorene
  • ethyl 2-(9H-fluoren-9-yl)acetate
  • 4-[2-[[2-(9H-fluoren-9-yl)acetyl]amino]ethyl]benzoic acid
  • diethyl-[2-[2-(9H-fluoren-9-yl)acetyl]oxyethyl]azanium,chloride

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Structural basis for the potent calpain inhibitory activity of peptidyl alpha-ketoacids.

J. Med. Chem. 51(14) , 4346-50, (2008)

A series of peptidyl alpha-ketoacids and alpha-ketoesters was synthesized and studied as mu-calpain inhibitors. Docking studies revealed that the mu-calpain inhibitory activity of the compounds is inf...

Prolonged pheromonotropic activity of pseudopeptide mimics of insect pyrokinin neuropeptides after topical application or injection into a moth.

Regul. Pept. 72(2-3) , 161-7, (1997)

Amphiphilic pseudopeptide analogs of Phe-Thr-Pro-Arg-Leu-NH2, representing the active C-terminal core pentapeptide of the pyrokinin class of insect neuropeptides, were synthesized by replacement of ph...

Direct determination of adamantanamine in plasma and urine with automated solid phase derivatization.

J. Chromatogr. A. 619(1) , 93-101, (1993)

A simple, highly sensitive and selective method is described for adamantanamine determination in plasma and urine by high-performance liquid chromatography with fluorescence detection. The method invo...


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Related Compounds

  • 9-fluorenylacetate
  • Ani9
  • 9H-Purine-9-acetic acid, 6-[(p-chlorophenyl)amino)-, ethyl ester
  • 9H-Purine-9-acetic acid, 1,6-dihydro-2-'(2-Methyl-1-oxopropyl)aMino-6-oxo-
  • 9H-Thioxanthene-9-acetic acid
  • 9H-Purine-9-acetic acid, 6-[bis[(1,1-diMethylethoxy)carbonyl]aMino]-