1-(4-nitrophenyl)-3-pyrrolidin-1-yl-propan-1-one hydrochloride

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Names

[ CAS No. ]:
6287-76-9

[ Name ]:
1-(4-nitrophenyl)-3-pyrrolidin-1-yl-propan-1-one hydrochloride

Chemical & Physical Properties

[ Density]:
1.21g/cm3

[ Boiling Point ]:
401.5ºC at 760 mmHg

[ Molecular Formula ]:
C13H17ClN2O3

[ Molecular Weight ]:
284.73900

[ Flash Point ]:
196.6ºC

[ Exact Mass ]:
284.09300

[ PSA ]:
66.13000

[ LogP ]:
3.52650

[ Index of Refraction ]:
1.571

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UH4388500
CHEMICAL NAME :
Propiophenone, 4'-nitro-3-(1-pyrrolidinyl)-, monohydrochloride
CAS REGISTRY NUMBER :
6287-76-9
LAST UPDATED :
198509
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C13-H16-N2-O3.Cl-H
MOLECULAR WEIGHT :
284.77

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
125 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 103,165,1964

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • trioxane
  • Pyrrolidine,hydrochloride (1:1)
  • 4-Nitroacetophenone

DownStream

Related Compounds

  • 2-((5-(3,4-dichlorophenyl)-1-(4-(difluoromethoxy)phenyl)-1H-imidazol-2-yl)thio)acetonitrile
  • N-(4-methylthiazol-2-yl)-2-((1-(o-tolyl)-5-(p-tolyl)-1H-imidazol-2-yl)thio)acetamide
  • N-(5-methyl-1,3,4-thiadiazol-2-yl)-2-((1-(o-tolyl)-5-(p-tolyl)-1H-imidazol-2-yl)thio)acetamide
  • 4-[1-ethyl-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-N-[2-(4-morpholinyl)ethyl]-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
  • 2-(6-Methylbenzo[b]thiophene-2-yl)-3-oxa-1-azaspiro[4,4]non-1-ene-4-one
  • ethyl 2-((5-(3,4-dichlorophenyl)-1-(4-(difluoromethoxy)phenyl)-1H-imidazol-2-yl)thio)acetate
  • 2-((5-(3,4-dichlorophenyl)-1-(4-(difluoromethoxy)phenyl)-1H-imidazol-2-yl)thio)-1-(piperidin-1-yl)ethanone
  • N-(4-chlorophenyl)-2-((5-(3,4-dichlorophenyl)-1-(4-(difluoromethoxy)phenyl)-1H-imidazol-2-yl)thio)acetamide
  • 5-(4-bromophenyl)-1-(4-(difluoromethoxy)phenyl)-2-(methylthio)-1H-imidazole
  • 5-(4-bromophenyl)-1-(4-(difluoromethoxy)phenyl)-2-(isobutylthio)-1H-imidazole