Methyl methoxyacetate

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Names

[ CAS No. ]:
6290-49-9

[ Name ]:
Methyl methoxyacetate

[Synonym ]:
Acetic acid, 2-methoxy-, methyl ester
Methyl methoxyacetate
EINECS 228-539-9
MFCD00008451

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
131.0±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C4H8O3

[ Molecular Weight ]:
104.104

[ Flash Point ]:
34.1±11.4 °C

[ Exact Mass ]:
104.047340

[ PSA ]:
35.53000

[ LogP ]:
0.01

[ Vapour Pressure ]:
9.5±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.379

[ Storage condition ]:
Flammables area

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AI8910000
CHEMICAL NAME :
Acetic acid, methoxy-, methyl ester
CAS REGISTRY NUMBER :
6290-49-9
BEILSTEIN REFERENCE NO. :
1742944
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C4-H8-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg/10M
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NDRC** National Defense Research Committee, Office of Scientific Research and Development, Progress Report. Volume(issue)/page/year: NDCrc-132,Feb,1942

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R10

[ Safety Phrases ]:
S16-S29-S33

[ RIDADR ]:
UN 3272 3/PG 3

[ WGK Germany ]:
2

[ RTECS ]:
AI8910000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
29189090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methanol
  • 2-Methoxyacetic acid
  • carbon monoxide
  • Sodium Methylate
  • Methyl bromoacetate
  • methyl chloroacetate
  • Methoxyacetyl chloride
  • dimethoxymethane
  • trioxane
  • Dibromomethane

DownStream

  • 1-(3,5-difluoropyridin-2-yl)-2-methoxyethanone
  • 1-methoxy-2-methyl-2-propanol
  • Methyl 4-methoxyacetoacetate
  • methyl 3-hydroxy-2-methoxy-3-(4-(trifluoromethyl)phenyl)acrylate
  • 4-(Trifluoromethyl)benzoic acid
  • Cyclohexanone
  • Methyl glyoxylate
  • dimethyl methoxymalonate
  • L-1-Phenylethylamine

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Predicting and avoiding subcellular compartmentalization artifacts arising from acetoxymethyl ester calcium imaging probes. The case of fluo-3 AM and a general account of the phenomenon including a problem avoidance chart.

Biotech. Histochem. 87(7) , 468-83, (2012)

Stimulated by difficulties experienced when using fluo-3 AM, we developed a general mechanistic model to aid understanding and practical application of calcium probes applied as acetoxymethyl (AM) est...

[Information from the Soviet Toxicology Center].

Farmakol. Toksikol. 43(6) , 750-1, (1980)

Regional difference in stainability with calcium-sensitive acetoxymethyl-ester probes in mouse brain slices.

Int. J. Neurosci. 119(2) , 214-26, (2009)

Loading neurons with membrane permeable Ca2+ indicators is a core experimental procedure in functional multineuron Ca2+ imaging (fMCI), an optical technique for monitoring multiple neuronal activities...


More Articles

Related Compounds

  • Methyl methoxyacetate
  • Methyl methoxyacetate
  • methyl α-hydroperoxy-α-methoxyacetate
  • methyl α-(2-nitrophenoxy)-α-methoxyacetate
  • METHYL 2,2-DICHLORO-2-METHOXYACETATE
  • Methyl 2-[(allyloxycarbonyl)amino]-2-methoxyacetate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 2-(Benzylthio)-1-(4-(((4-methoxyphenyl)thio)methyl)piperidin-1-yl)ethanone
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide