Methyl carbazate

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Names

[ CAS No. ]:
6294-89-9

[ Name ]:
Methyl carbazate

[Synonym ]:
Carbazic acid methyl ester
EINECS 228-560-3
methyl N-aminocarbamate
Hydrazinecarboxylic acid, methyl ester
MFCD00007594
Methyl hydrazinecarboxylate
Methyl carbazate

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
230.9±0.0 °C at 760 mmHg

[ Melting Point ]:
70-73 °C(lit.)

[ Molecular Formula ]:
C2H6N2O2

[ Molecular Weight ]:
90.081

[ Flash Point ]:
86.1±18.7 °C

[ Exact Mass ]:
90.042931

[ PSA ]:
64.35000

[ LogP ]:
-0.79

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.435

[ Water Solubility ]:
soluble

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
T:Toxic;Xi:Irritant;

[ Risk Phrases ]:
R23/25;R36/37/38;R48

[ Safety Phrases ]:
S26-S37/39-S45-S38-S36/37/39-S22

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2928000090

Synthetic Route

Precursor & DownStream

Precursor

  • Dimethyl Carbonate
  • methyl N-nitrocarbamate
  • Methyl chloroformate
  • methyl (phenylseleno)formate
  • acetic acid

DownStream

  • 3-(4-semicarbazido)propyltriethoxysilane
  • methyl N-[(2-phenylacetyl)amino]carbamate
  • Methyl hydrazidodicarboxylate
  • carbohydrazide
  • 4-(4-Chlorophenyl)-1H-1,2,4-triazol-5(4H)-one
  • Hydrazinecarboxamide,N-hydroxy-
  • 4-(4-FLUOROPHENYL)-1H-1,2,4-TRIAZOL-5(4H)-ONE
  • methyl formate
  • Benzenepropanoic acid, β-oxo-, methyl ester
  • methyl (3R)-3-hydroxy-3-phenyl-propanoate

Customs

[ HS Code ]: 2928000090

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Imidazo[1,5-d][1,2,4]triazines as potential antiasthma agents.

J. Med. Chem. 28(11) , 1704-16, (1985)

By using inhibition of histamine release from antigen-challenged, sensitized human basophils as a means of identifying a potentially prophylactic drug for the treatment of asthma, a series of substitu...

Methyl 3-(4-methyl-benzyl-idene)carbazate.

Acta Crystallogr. Sect. E Struct. Rep. Online 66(Pt 6) , o1429, (2010)

The title compound, C(10)H(12)N(2)O(2), was prepared by the reaction of methyl carbazate and 4-methyl-benzaldehyde. The dihedral angle between the benzene ring and the carbazate fragment is 20.86 (10)...

Negative results of carcinogenicity bioassay of methyl carbazate in rats: significance for the toxicological evaluation of carbadox.

Toxicology 22(3) , 219-21, (1981)

Methyl carbazate, a metabolite of carbadox in the rat, was administered orally to rats for 2 years. The compound was mixed in the diet at concentrations corresponding to dose levels of 0, 2.5, 5 and 1...


More Articles


Related Compounds

  • methyl carbazate
  • N-t-butoxycarbonyl-N'-4-hydroxybenzyl hydrazine
  • 2-Methyl-2-propanyl 2-(4-cyanobenzyl)hydrazinecarboxylate
  • methyl (2-hydroxy-1-phenylethylidene)carbazate
  • methyl (3S)-3-hydroxy-5-methylhexanoate
  • methyl 6-(2-hydroxyethoxy)hexanoate