aspirin DL-lysine salt

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Names

[ CAS No. ]:
62952-06-1

[ Name ]:
aspirin DL-lysine salt

[Synonym ]:
Acetylsalicylate Lysine
EINECS 263-769-3
Acetylsalicylic acid lysine salt
MFCD00864299
2-(acetyloxy)benzoic acid - lysine (1:1)
aspirin DL-lysine salt
Lysine acetylsalicylate
6-Ammonionorleucine 2-acetoxybenzoate
DL-lysine 2-(Acetyloxy)benzoate
DL-Lysine acetylsalicylic acid salt
Benzoic acid, 2-(acetyloxy)-, compd. with lysine (1:1)
DL-Lysine acetylsalicylate

Chemical & Physical Properties

[ Boiling Point ]:
321.4ºC at 760 mmHg

[ Melting Point ]:
154-156ºC

[ Molecular Formula ]:
C15H22N2O6

[ Molecular Weight ]:
326.345

[ Flash Point ]:
131.2ºC

[ Exact Mass ]:
326.147797

[ PSA ]:
152.94000

[ LogP ]:
2.23800

[ Storage condition ]:
-20°C Freezer

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OL5675000
CHEMICAL NAME :
Lysine, monosalicylate acetate (ester), DL-
CAS REGISTRY NUMBER :
62952-06-1
LAST UPDATED :
199706
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C9-H8-O4.C6-H14-N2-O2
MOLECULAR WEIGHT :
326.39

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4350 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 6,1275,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1860 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 6,1275,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1525 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 6,1275,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3270 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 6,1275,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 21,341,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
950 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 6,1275,1978

Safety Information

[ HS Code ]:
2922509090

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%


Related Compounds

  • poly-DL-lysine hydrobromide
  • POLY-DL-LYSINE HYDROBROMIDE
  • diatrizoic acid lysine salt
  • Reparixin L-lysine salt
  • REPERTAXIN L-LYSINE SALT
  • DL-Lysine Dihydrochloride
  • 1-[1-(4,4-Dimethylcyclohexyl)cyclopropyl]ethan-1-ol
  • Sodium 3-methyl-5-nitrobenzene-1-sulfinate
  • 2-[N-(2,2-dimethylpropyl)-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,3-dimethylbutanamido]acetic acid
  • 1-(2-Methylpiperidin-3-yl)-4-(2-methylpropyl)piperazine
  • 2-bromo-N-[3-(dimethylamino)-2,2-dimethylpropyl]-N-methylacetamide
  • 5-chloro-1-(cyclobutylmethyl)-1H-1,2,3-benzotriazole
  • 4-[(cyclopropylmethoxy)carbamoyl]-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
  • 1-({imidazo[1,2-a]pyridin-3-yl}methyl)-N-methylcyclopropan-1-amine
  • 3-(2-Isocyanatoethyl)thiolane
  • 3-{Imidazo[1,2-a]pyridin-3-yl}propanal
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