DL-Dopa

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Names

[ CAS No. ]:
63-84-3

[ Name ]:
DL-Dopa

[Synonym ]:
EINECS 200-566-0
<small>DL</small>-3-(3,4-Dihydroxyphenyl)alanine
MFCD00063060
Tyrosine, 3-hydroxy-

Chemical & Physical Properties

[ Density]:
1.468 g/cm3

[ Boiling Point ]:
448.39ºC at 760 mmHg

[ Melting Point ]:
270-272ºC(lit.)

[ Molecular Formula ]:
C9H11NO4

[ Molecular Weight ]:
197.18800

[ Flash Point ]:
224.978ºC

[ Exact Mass ]:
197.06900

[ PSA ]:
103.78000

[ LogP ]:
0.75250

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AY5250000
CHEMICAL NAME :
Alanine, 3-(3,4-dihydroxyphenyl)-, DL-
CAS REGISTRY NUMBER :
63-84-3
LAST UPDATED :
199504
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H11-N-O4
MOLECULAR WEIGHT :
197.21
WISWESSER LINE NOTATION :
QVYZ1R CQ DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1293 No. of Facilities: 10 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 59 (estimated) No. of Female Employees: 59 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AY5250000

Precursor & DownStream

Precursor

  • (2S)-2-benzamido-3-(3,4-dimethoxyphenyl)propanoic acid
  • Levodopa
  • Water
  • N-benzoyl-β-(4-hydroxy-3-methoxyphenyl)-alaninamide
  • 2-acetamido-3-(3,4-dimethoxyphenyl)prop-2-enoic acid
  • ACETIC ACID 2-METHOXY-4-(5-OXO-2-PHENYL-OXAZOL-4-YLIDENEMETHYL)-PHENYL ESTER
  • D-Thr-OH
  • DL-Phenylalanine
  • 2-benzamido-3-(4-hydroxy-3-methoxyphenyl)propanoic acid

DownStream

  • Levodopa
  • D-dopa
  • 2-Amino-3-(2-fluoro-4,5-dihydroxyphenyl)propanoic acid
  • 5,6-dihydroxyindole-2-carboxylic acid
  • 5-[(3,4-dihydroxyphenyl)methyl]imidazolidine-2,4-dione
  • Tyrosine, 3-hydroxy-,methyl ester, hydrochloride (1:1)

Articles

Bone metastases radiopharmaceuticals: an overview.

Curr. Radiopharm. 6(1) , 41-7, (2013)

The skeleton is one of the preferential sites for metastases of solid tumors, and metastatic disease is the most common malignancy of the bone. Diagnosis and evaluation of skeletal metastases require ...

Stability of polydopamine and poly(DOPA) melanin-like films on the surface of polymer membranes under strongly acidic and alkaline conditions

Colloids Surf. B Biointerfaces 110 , 22-8, (2013)

This study investigated the stability of polydopamine and poly(3,4-dihydroxyphenylalanine) (poly(DOPA)) melanin-like films on the surface of polymer substrates. Three polymer membranes, polypropylene ...

Mussel adhesion is dictated by time-regulated secretion and molecular conformation of mussel adhesive proteins.

Nat. Commun. 6 , 8737, (2015)

Interfacial water constitutes a formidable barrier to strong surface bonding, hampering the development of water-resistant synthetic adhesives. Notwithstanding this obstacle, the Asian green mussel Pe...


More Articles


Related Compounds

  • 6-HO-DL-DOPA
  • 6-Hydroxy-DL-DOPA
  • Di-O-Methyl α-Ethyl DL-DOPA
  • DL-dopa methyl ester hydrochloride
  • 6-Fluoro DL-DOPA Hydrobromide Salt
  • DL-1-N-Benzyloxycarbonylamino-dodecandisaeure-(1,12)-dimethylester