6,12b-Dihydro-3-Methylcholanthrene

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Names

[ CAS No. ]:
63041-50-9

[ Name ]:
6,12b-Dihydro-3-Methylcholanthrene

[Synonym ]:
meso-Dihydro-3-methylcholanthrene
Cholanthrene,6,12b-dihydro-3-methyl
3-Methyl-6,12b-dihydrocholanthracen

Chemical & Physical Properties

[ Density]:
1.173g/cm3

[ Boiling Point ]:
434.8ºC at 760 mmHg

[ Molecular Formula ]:
C21H18

[ Molecular Weight ]:
270.36800

[ Flash Point ]:
210.7ºC

[ Exact Mass ]:
270.14100

[ LogP ]:
5.13050

[ Index of Refraction ]:
1.694

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FZ3150000
CHEMICAL NAME :
Cholanthrene, 6,12b-dihydro-3-methyl-
CAS REGISTRY NUMBER :
63041-50-9
BEILSTEIN REFERENCE NO. :
3332091
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C21-H18
MOLECULAR WEIGHT :
270.39
WISWESSER LINE NOTATION :
L E6 D6656 1A T&&TT&J R1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
40 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Tumorigenic - tumors at site of application
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 1,695,1941
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 1,685,1941

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-Methylcholanthrene
  • Diethyl ether
  • benzene

DownStream

  • 3-Methylcholanthrene

Related Compounds

  • 3,6-dihydro-3,5,6-triphenyl-3,6-epidioxypyrazin-2(1H)-one
  • 5,6-Dihydro-3-imino-8,9-dimethoxythiazolo[4,3-a]isoquinoline-1-carbonitrile
  • 5,6-dihydro-3,6-diphenyl-4H-6-(N-methylanilino)-1,2,5-oxadiazine
  • 5,6-Dihydro-3-allyloxy-11-ethyl-12-phenyldibenzo[a,e]cyclooctene
  • 5,6-Dihydro-3-methyl-6-(4-nitrophenyl)-4H-pyrrolo(1,2-a)thieno(3,2-f)(1,4)diazepine
  • 5,6-Dihydro-3-methyl-5,5-dipropyl-2H-1,3-oxazine-2,4(3H)-dione
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • 2-[4-(2-bromobenzoyl)piperazin-1-yl]-N-ethyl-6-methylpyrimidin-4-amine