Methyl 2-chloro-5-nitrobenzoate

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Names

[ CAS No. ]:
6307-82-0

[ Name ]:
Methyl 2-chloro-5-nitrobenzoate

[Synonym ]:
Benzoic acid, 2-chloro-5-nitro-, methyl ester
Methyl 2-chloro-5-nitrobenzenecarboxylate
Methyl 2-chloro-5-nitrobenzoate
4-Chloro-3-(methoxycarbonyl)nitrobenzene
2-Chloro-1-methoxycarbonyl-5-nitrobenzene
Methylester kyseliny 2-chlor-5-nitrobenzoove [Czech]
2-Chloro-5-nitrobenzoic acid methyl ester
methyl ester of 2-chloro-5-nitrobenzoic acid
MFCD00184587
methyl 2-chloro-5-nitro-benzoate
2-methoxycarbonyl-4-nitrochlorobenzene
BENZOIC ACID,2-CHLORO-5-NITRO-,METHYL ESTER

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
316.7±22.0 °C at 760 mmHg

[ Melting Point ]:
69-73 °C(lit.)

[ Molecular Formula ]:
C8H6ClNO4

[ Molecular Weight ]:
215.590

[ Flash Point ]:
145.3±22.3 °C

[ Exact Mass ]:
214.998535

[ PSA ]:
72.12000

[ LogP ]:
2.16

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.568

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG5426500
CHEMICAL NAME :
Benzoic acid, 2-chloro-5-nitro-, methyl ester
CAS REGISTRY NUMBER :
6307-82-0
BEILSTEIN REFERENCE NO. :
1966320
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C8-H6-Cl-N-O4
MOLECULAR WEIGHT :
215.60

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,591,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,591,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5360 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,591,1986

Safety Information

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ WGK Germany ]:
2

[ RTECS ]:
DG5426500

Synthetic Route

Precursor & DownStream

Precursor

  • Methanol
  • 2-Chloro-5-nitrobenzoic acid
  • 2-Chloro-5-nitrobenzoyl chloride
  • 2-Chlorobenzoic acid
  • 2-Chloroaniline
  • Methyl 2-chlorobenzoate
  • 2-Chlorobenzonitrile
  • 2-chloro-N-(4-chlorophenyl)-5-nitrobenzamide
  • diazomethane
  • nitric acid

DownStream

  • Methyl 5-amino-2-chlorobenzoate
  • Methyl 2-fluoro-5-nitrobenzoate
  • methyl 5-amino-2-morpholinobenzenecarboxylate
  • methyl 5-amino-2-(4-aminophenyl)sulfonylbenzoate
  • methyl 3-hydroxy-5-nitrobenzo[b]thiophene-3-carboxylate
  • METHYL 2-MORPHOLINO-5-NITROBENZENECARBOXYLATE
  • Methyl 2-(cyclohexylamino)-5-nitrobenzoate
  • 2-(2-methoxyanilino)-5-nitrobenzoic acid

Related Compounds

  • Methyl 2-chloro-5-methyl-4-nitrobenzoate
  • methyl 2-chloro-5-methoxy-4-nitrobenzoate
  • methyl 2-chloro-5-iodo-3-nitrobenzoate
  • Methyl 2-chloro-4-hydroxy-5-nitrobenzoate
  • Methyl 2-chloro-4-methyl-5-nitrobenzoate
  • Methyl 2-chloro-4-fluoro-5-nitrobenzoate
  • 3-Cyclopropoxy-6-ethyl-N-methylpicolinamide
  • 6-(4-Bromophenyl)-4-methyl-2-(3-methylbutyl)-4a,7,8,9a-tetrahydropurino[7,8-a]imidazole-1,3-dione
  • 2-(1-(3-chlorobenzyl)azetidin-3-yl)-5-methyl-1H-benzo[d]imidazole oxalate
  • 3-AMino-4-hydroxybenzenesulfonic Acid Hydrate
  • 2-(2-Methoxyethyl)-6-(2-methoxyphenyl)-4-methyl-4a,7,8,9a-tetrahydropurino[7,8-a]imidazole-1,3-dione
  • 1-[[1,3-dimethyl-2,6-dioxo-7-(2-oxopropyl)-5H-purin-7-ium-8-yl]methyl]piperidine-4-carboxamide
  • 3-fluoro-N-((2-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)methyl)-4-methoxybenzenesulfonamide
  • 2-(1-(3,5-dimethoxybenzyl)azetidin-3-yl)-5-methyl-1H-benzo[d]imidazole oxalate
  • 3-(Cyclohexylmethyl)-4-methylphenol
  • 2-(1-(3,4-difluorobenzyl)azetidin-3-yl)-5-methyl-1H-benzo[d]imidazole oxalate