2-methyl-11-oxopyrido[2,1-b]quinazoline-8-carboxylic acid

Names

[ CAS No. ]:
63094-33-7

[ Name ]:
2-methyl-11-oxopyrido[2,1-b]quinazoline-8-carboxylic acid

[Synonym ]:
11H-Pyrido(2,1-b)quinazoline-8-carboxylic acid,2-methyl-11-oxo
2-Methyl-11-oxo-11H-pyrido(2,1-b)quinazoline-8-carboxylic acid

Chemical & Physical Properties

[ Density]:
1.42g/cm3

[ Boiling Point ]:
457.9ºC at 760 mmHg

[ Molecular Formula ]:
C14H10N2O3

[ Molecular Weight ]:
254.24100

[ Flash Point ]:
230.7ºC

[ Exact Mass ]:
254.06900

[ PSA ]:
71.67000

[ LogP ]:
1.85430

[ Index of Refraction ]:
1.695

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UV1176440
CHEMICAL NAME :
11H-Pyrido(2,1-b)quinazoline-8-carboxylic acid, 2-methyl-11-oxo-
CAS REGISTRY NUMBER :
63094-33-7
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C14-H10-N2-O3
MOLECULAR WEIGHT :
254.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #3902639
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #3902639

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • 2-({[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}oxy)propanoic acid
  • 2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methoxypropanamido]-3-methoxy-2-methylpropanoic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • {1-[3-(difluoromethyl)-1-methyl-1H-pyrazol-4-yl]-2,2-difluorocyclopropyl}methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 4-methyl-1-(1-methyl-1H-pyrazol-5-yl)cyclohex-2-en-1-ol
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide