2-Acetyl-5-chlorothiophene

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Names

[ CAS No. ]:
6310-09-4

[ Name ]:
2-Acetyl-5-chlorothiophene

[Synonym ]:
1-(5-chlorothiophen-2-yl)ethanone
Ethanone, 1- (5-chloro-2-thienyl)-
1-(5-Chloro-2-thienyl)ethanone
2-Acetyl-5-chlorothiophene
EINECS 228-630-3
Ethanone, 1-(5-chloro-2-thienyl)-
MFCD00005444

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
233.3±0.0 °C at 760 mmHg

[ Melting Point ]:
46-49 °C(lit.)

[ Molecular Formula ]:
C6H5ClOS

[ Molecular Weight ]:
160.621

[ Flash Point ]:
108.3±0.0 °C

[ Exact Mass ]:
159.974960

[ PSA ]:
45.31000

[ LogP ]:
2.15

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.560

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OB1745000
CHEMICAL NAME :
Ketone, 5-chloro-2-thienyl methyl
CAS REGISTRY NUMBER :
6310-09-4
BEILSTEIN REFERENCE NO. :
0113936
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C6-H5-Cl-O-S
MOLECULAR WEIGHT :
160.62
WISWESSER LINE NOTATION :
T5SJ BV1 EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
500 mg/kg
SEX/DURATION :
male 20 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
ANREAK Anatomical Record. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1906/08- Volume(issue)/page/year: 125,312,1956

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
F+

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
UN2811

[ WGK Germany ]:
3

[ RTECS ]:
OB1745000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Chlorothiophene
  • Ethanoic anhydride
  • Acetyl chloride
  • 2-Acetylthiophene
  • Methyl 2-thienyl ketone oxime
  • 2-ACETYLTHIOPHENE O-METHYLOXIME

DownStream

  • 5-Chlorothiophene-2-carbonyl chloride
  • 1-(5-Morpholinothiophen-2-Yl)Ethanone
  • ethyl 3-(5-chlorothiophen-2-yl)-3-oxopropanoate
  • 2-acetyl-5-cyanothiophene
  • 1-(5-Iodo-2-thienyl)ethanone
  • 5-chlorothiophene-2-carboxamide
  • 5-Chloro-2-thiophenecarboxylic acid
  • 2-Acetylthiophene
  • Ethanone, 1,1'-[2,2'-bithiophene]-5,5'-diylbis-
  • 2-bromo-1-(5-chlorothiophen-2-yl)ethanone

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Structural correlation of some heterocyclic chalcone analogues and evaluation of their antioxidant potential.

Molecules 18(10) , 11996-2011, (2013)

A series of six novel heterocyclic chalcone analogues 4(a-f) has been synthesized by condensing 2-acetyl-5-chlorothiophene with benzaldehyde derivatives in methanol at room temperature using a catalyt...

Experimental and theoretical FT-IR, Raman and XRD study of 2-acetyl-5-chlorothiophene.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 127 , 67-73, (2014)

The structure of 2-acetyl-5-chlorothiophene (ACT) has been characterized by FT-IR, Raman and single-crystal X-ray diffraction techniques. The isomers, optimized geometric parameters, normal mode frequ...


More Articles

Related Compounds

  • 2-Acetyl-5-chlorothiophene
  • 2-acetyl-5-chloro-1H-indole-3-carboxylic acid
  • 2-acetyl-5,8-dimethoxy-3-methylnaphthalen-1-yl acetate
  • 2-Acetyl-5,6-dihydro-5-methyl-11H-dibenz[b,e]azepin-11-one
  • 2-Acetyl-5-(2-carbomethoxy-6-methoxybenzoyloxy)-1,2,3,4-tetrahydronaphthalene
  • 2-acetyl-5-methoxy-1H-indole-3-carboxylic acid