(2,5-Dioxotetrahydro-3-furanyl)acetic acid

Suppliers

Names

[ CAS No. ]:
6318-55-4

[ Name ]:
(2,5-Dioxotetrahydro-3-furanyl)acetic acid

[Synonym ]:
(2,5-Dioxo-2,5-dihydro-furan-3-yl)-acetic acid
EINECS 228-663-3
cis-acotinic anyhydride
cis-Aconitic acid anhydride
3-Furanacetic acid, tetrahydro-2,5-dioxo-
propene-1,2,3-tricarboxylic acid-1,2-anhydride
cis-Aconitic anhydride
cis-Propene-1,2,3-tricarboxylic anhydride
Aconitic anhydride
3-Furanacetic acid,2,5-dihydro-2,5-dioxo
MFCD00005524
(2,5-Dioxotetrahydro-3-furanyl)acetic acid
(Z)-Aconitic anhydride
carboxymethylmaleic anhydride

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
439.9±18.0 °C at 760 mmHg

[ Melting Point ]:
75-78 °C(lit.)

[ Molecular Formula ]:
C6H4O5

[ Molecular Weight ]:
158.109

[ Flash Point ]:
194.6±14.7 °C

[ Exact Mass ]:
158.021530

[ PSA ]:
80.67000

[ LogP ]:
-1.61

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.506

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2918300090

Synthetic Route

Precursor & DownStream

Precursor

  • 1-Propene-1,2,3-tricarboxylic acid
  • cis-Aconitic acid

DownStream

  • cis-Aconitic acid
  • Itaconic anhydride
  • 2-(3,6-DIOXO-1,2,3,6-TETRAHYDROPYRIDAZIN-4-YL)ACETIC ACID
  • aconityldoxorubicin

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Enhanced shRNA delivery and ABCG2 silencing by charge-reversible layered nanocarriers.

Small 11(8) , 952-62, (2015)

Polycationic vectors have been used to deliver short hairpin RNAs (shRNAs) to knock-down genes for cancer therapies, but their inefficiency in lysosomal escape and shRNA release causes their low gene ...

Development of biodegradable polymeric implants of RGD-modified PEG-PAMAM-DOX conjugates for long-term intratumoral release.

Drug Deliv. 22 , 389-99, (2015)

The sustained release implants can be directly implanted in tumor site by surgery and are promising for cancer treatment.RGD-modified PEGylated polyamidoamine (PAMAM) dendrimer with doxorubicin (DOX) ...

Acid-responsive PEGylated doxorubicin prodrug nanoparticles for neuropilin-1 receptor-mediated targeted drug delivery.

Colloids Surf. B Biointerfaces 136 , 365-74, (2015)

Self-assembled prodrug nanoparticles have demonstrated great promise in cancer chemotherapy. In the present study, we developed a new kind of prodrug nanoparticles for targeted drug delivery. PEGylate...


More Articles


Related Compounds

  • 2-[5-(3-bromophenyl)tetrazol-2-yl]acetic acid
  • 2-[5-(3,5-dichlorobenzoyl)-2-hydroxyphenyl]acetic acid
  • 2-[5-(3-methylbut-2-enoxy)-2-propanoylphenoxy]acetic acid
  • 2-[5-[3-(6-benzoylnaphthalen-2-yl)oxypropoxy]indol-1-yl]acetic acid
  • 2-[5-(3,5-dichlorophenyl)sulfanyl-1-methyl-4-propan-2-ylimidazol-2-yl]acetic acid
  • 2-[[5-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid