Tetrabromophthalic anhydride

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Names

[ CAS No. ]:
632-79-1

[ Name ]:
Tetrabromophthalic anhydride

[Synonym ]:
MFCD00005919
4,5,6,7-tetrabromo-2-benzofuran-1,3-dione
EINECS 211-185-4

Chemical & Physical Properties

[ Density]:
2.771 g/cm3

[ Boiling Point ]:
540.5ºC at 760 mmHg

[ Melting Point ]:
269-271 °C(lit.)

[ Molecular Formula ]:
C8Br4O3

[ Molecular Weight ]:
463.70000

[ Flash Point ]:
280.7ºC

[ Exact Mass ]:
459.65800

[ PSA ]:
43.37000

[ LogP ]:
4.04720

[ Vapour Pressure ]:
0.11 mm Hg ( 180 °C)

[ Index of Refraction ]:
1.725

[ Water Solubility ]:
hydrolysis

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TI3350000
CHEMICAL NAME :
Phthalic anhydride, tetrabromo-
CAS REGISTRY NUMBER :
632-79-1
BEILSTEIN REFERENCE NO. :
0018908
LAST UPDATED :
199806
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C8-Br4-O3
MOLECULAR WEIGHT :
463.72

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0523271 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0539755
TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>10920 mg/m3/4H
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0522251
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0522251
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0521611 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2 gm/m3/4H/3W-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - changes in lung weight Gastrointestinal - changes in structure or function of salivary glands Liver - changes in liver weight
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0523277
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
100 gm/kg/4W-I
TOXIC EFFECTS :
Behavioral - ataxia Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0523276

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H317

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
TI3350000

[ HS Code ]:
29173911

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Phthalic anhydride
  • 3,4,5,6-Tetrabromophthalic acid
  • Sulfuric acid
  • Bromine

DownStream

  • 5,6,7,8-tetrabromo-4-(4-methylphenyl)-2,3-benzoxazin-1-one
  • 1H-Isoindole-1,3(2H)-dione,4,5,6,7-tetrabromo-2-(2-thiazolyl)-
  • Benzoic acid,2,3,4,5-tetrabromo-6-[(2-thiazolylamino)carbonyl]-
  • 1H-Isoindole-1,3(2H)-dione,4,5,6,7-tetrabromo-
  • 4,5,6,7-tetrabromo-2-(2-hydroxyethyl)isoindole-1,3-dione
  • 3,4,5,6-Tetrabromophthalic acid
  • 4,5,6,7-Tetrabromophenolphthalein
  • Coumarin-3-carbonitrile
  • 1H-Isoindole-1,3(2H)-dione,2-amino-4,5,6,7-tetrabromo-
  • 2,3,4,5-tetrabromo-6-(4-hydroxy-3,5-dimethylbenzoyl)benzoic acid

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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