Wogonin

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Names

[ CAS No. ]:
632-85-9

[ Name ]:
Wogonin

[Synonym ]:
Norwogonin 8-methyl ether
5,7-DIHYDROXY-8-METHOXYFLAVON
5,7-Dihydroxy-8-methoxy-2-phenyl-chromen-4-on
Wogonin
5,7-Dihydroxy-8-methoxy-2-phenyl-4H-chromen-4-one
5,7-dihydroxy-8-methoxy-2-phenyl-chromen-4-one
4H-1-Benzopyran-4-one, 5,7-dihydroxy-8-methoxy-2-phenyl-
MFCD00017736
5,7-dihydroxy-8-methoxyflavone
vogonin
WOOGONIN
WILDYAMP.E

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
518.8±50.0 °C at 760 mmHg

[ Melting Point ]:
203-206°C

[ Molecular Formula ]:
C16H12O5

[ Molecular Weight ]:
284.263

[ Flash Point ]:
198.4±23.6 °C

[ Exact Mass ]:
284.068481

[ PSA ]:
79.90000

[ LogP ]:
2.14

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.669

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LK8331000
CHEMICAL NAME :
Flavone, 5,7-dihydroxy-8-methoxy-
CAS REGISTRY NUMBER :
632-85-9
BEILSTEIN REFERENCE NO. :
0287152
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H12-O5
MOLECULAR WEIGHT :
284.28
WISWESSER LINE NOTATION :
T66 BO EVJ CR& GQ IQ JO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
20 nmol/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 135,77,1984

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
3145

[ RTECS ]:
SJ8922500

[ Packaging Group ]:
III

[ Hazard Class ]:
8

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 7-hydroxy-5,8-dimethoxy-2-phenylchromen-4-one
  • Antiarol
  • 3-phenyl-1-(2,4,6-trihydroxy-3-methoxyphenyl)prop-2-en-1-one
  • 2,3,4-trimethoxy-6-hydroxyacetophenone
  • Norwogonin
  • methyl iodide
  • (2E)-1-(6-hydroxy-2,3,4-trimethoxyphenyl)-3-phenyl-2-Propen-1-one
  • Ciprofloxacin Hydrochloride
  • 7-benzyloxy-5-hydroxy-8-methoxy-2-phenyl-chromen-4-one
  • 1-(2,4-dihydroxy-3,6-dimethoxy-phenyl)ethanone

DownStream

  • Baicalein
  • Moslosooflavone
  • Wogonoside
  • 5,7-Diacetoxy-8-methoxyflavone
  • 5-Hydroxy-7-acetoxy-8-methoxyflavone
  • Norwogonin

Related Compounds

  • 7-Benzyl-wogonin
  • wogonin diacetate
  • 5-O-methyl wogonin
  • Wogonin 7-O-glucuronide
  • 3',4'-Dihydroxy-wogonin
  • 3',4'-Dimethoxy-wogonin
  • 3,4,9-Trimethyl-1-(2-methylprop-2-enyl)-7-propyl-4,5a-dihydropurino[8,7-c][1,2,4]triazin-5-ium-6,8-dione
  • 2-(3-Methoxyphenyl)-5-[[4-(trifluoromethyl)phenyl]methyl]-1,2,3,3a-tetrahydropyrazolo[1,5-a]pyrazin-4-one
  • 3-(3-chloro-4-fluorophenyl)-N-[1-(1,3-dimethyl-2,4-dioxo-1,3-diazinan-5-yl)piperidin-4-yl]propanamide
  • N-[1-(1,3-dimethyl-2,4-dioxo-5H-pyrimidin-1-ium-5-yl)piperidin-4-yl]-2-(4-ethoxyphenyl)acetamide
  • 5-[3-(Azetidin-1-yl)-3-oxopropyl]-1,2,3,3a-tetrahydropyrazolo[1,5-a]pyrazin-4-one
  • 3,9-Dimethyl-1-(2-methylpropyl)-7-propyl-4,5a-dihydropurino[8,7-c][1,2,4]triazin-5-ium-6,8-dione
  • N-[1-(1,3-dimethyl-2,4-dioxo-5H-pyrimidin-1-ium-5-yl)piperidin-4-yl]-3-(4-methoxyphenyl)propanamide
  • N-[1-(1,3-dimethyl-2,4-dioxo-1,3-diazinan-5-yl)piperidin-4-yl]-3-(2-fluorophenyl)propanamide
  • N-[1-(1,3-dimethyl-2,4-dioxo-1,3-diazinan-5-yl)piperidin-4-yl]-2-(3-methylphenoxy)acetamide
  • 2-bromo-N-[1-(1,3-dimethyl-2,4-dioxo-5H-pyrimidin-1-ium-5-yl)piperidin-4-yl]benzamide
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