Wogonin

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Names

[ CAS No. ]:
632-85-9

[ Name ]:
Wogonin

[Synonym ]:
Norwogonin 8-methyl ether
5,7-DIHYDROXY-8-METHOXYFLAVON
5,7-Dihydroxy-8-methoxy-2-phenyl-chromen-4-on
Wogonin
5,7-Dihydroxy-8-methoxy-2-phenyl-4H-chromen-4-one
5,7-dihydroxy-8-methoxy-2-phenyl-chromen-4-one
4H-1-Benzopyran-4-one, 5,7-dihydroxy-8-methoxy-2-phenyl-
MFCD00017736
5,7-dihydroxy-8-methoxyflavone
vogonin
WOOGONIN
WILDYAMP.E

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
518.8±50.0 °C at 760 mmHg

[ Melting Point ]:
203-206°C

[ Molecular Formula ]:
C16H12O5

[ Molecular Weight ]:
284.263

[ Flash Point ]:
198.4±23.6 °C

[ Exact Mass ]:
284.068481

[ PSA ]:
79.90000

[ LogP ]:
2.14

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.669

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LK8331000
CHEMICAL NAME :
Flavone, 5,7-dihydroxy-8-methoxy-
CAS REGISTRY NUMBER :
632-85-9
BEILSTEIN REFERENCE NO. :
0287152
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H12-O5
MOLECULAR WEIGHT :
284.28
WISWESSER LINE NOTATION :
T66 BO EVJ CR& GQ IQ JO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
20 nmol/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 135,77,1984

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
3145

[ RTECS ]:
SJ8922500

[ Packaging Group ]:
III

[ Hazard Class ]:
8

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 7-hydroxy-5,8-dimethoxy-2-phenylchromen-4-one
  • Antiarol
  • 3-phenyl-1-(2,4,6-trihydroxy-3-methoxyphenyl)prop-2-en-1-one
  • 2,3,4-trimethoxy-6-hydroxyacetophenone
  • Norwogonin
  • methyl iodide
  • (2E)-1-(6-hydroxy-2,3,4-trimethoxyphenyl)-3-phenyl-2-Propen-1-one
  • Ciprofloxacin Hydrochloride
  • 7-benzyloxy-5-hydroxy-8-methoxy-2-phenyl-chromen-4-one
  • 1-(2,4-dihydroxy-3,6-dimethoxy-phenyl)ethanone

DownStream

  • Baicalein
  • Moslosooflavone
  • Wogonoside
  • 5,7-Diacetoxy-8-methoxyflavone
  • 5-Hydroxy-7-acetoxy-8-methoxyflavone
  • Norwogonin

Related Compounds

  • 2-(2,4-dioxo-1,3-diazaspiro[4.4]non-3-yl)-N-(1-methyl-1H-pyrazol-4-yl)acetamide
  • N-[2-(1,3-thiazol-2-yl)ethyl]-5-(2-thienyl)-1H-pyrazole-3-carboxamide
  • N-[3-(1H-benzimidazol-2-yl)propyl]-4-methyl-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxamide
  • 3-(4-hydroxy-6-methyl-2-oxopyridin-1(2H)-yl)-N-(1,3-thiazol-2-yl)propanamide
  • N~1~-(3-chlorobenzyl)-2-[3-(2-methoxyphenyl)-6-oxo-1(6H)-pyridazinyl]acetamide
  • 2-[5-(4-methoxyphenyl)-3-methyl-1H-pyrazol-4-yl]-N-[2-(1,3-thiazol-2-yl)ethyl]acetamide
  • N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-methyl-1H-indole-4-carboxamide
  • 1-[4-(Methylsulfonyl)piperazino]-6-(2-pyrimidinylamino)-1-hexanone
  • N-[2-(5-chloro-1H-indol-3-yl)ethyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide
  • 2'-cyclohexyl-N-cyclopropyl-1'-oxo-1',4'-dihydro-2'H-spiro[cyclohexane-1,3'-isoquinoline]-4'-carboxamide
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