Salsolidine hydrochloride

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Names

[ CAS No. ]:
63283-42-1

[ Name ]:
Salsolidine hydrochloride

[Synonym ]:
Salsolidine hydrochloride
Prestwick_860
Isoquinoline,6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro,hydrochloride
Salsolidin*HCl

Chemical & Physical Properties

[ Boiling Point ]:
313.4ºC at 760 mmHg

[ Melting Point ]:
189-192ºC

[ Molecular Formula ]:
C12H18ClNO2

[ Molecular Weight ]:
243.73

[ Flash Point ]:
127.1ºC

[ Exact Mass ]:
243.10300

[ PSA ]:
30.49000

[ LogP ]:
3.04130

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NX5018600
CHEMICAL NAME :
Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-methyl-, hydrochloride
CAS REGISTRY NUMBER :
63283-42-1
LAST UPDATED :
198806
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H17-N-O2.Cl-H
MOLECULAR WEIGHT :
243.76

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
189 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 76,263,1942

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 6,7-Dimethoxy-1-methyl-3,4-dihydroisoquinoline
  • Acetamide, N-(3,4-dimethoxyphenethyl)- (8CI)
  • 3,4-Dimethoxyphenethylamine

DownStream

  • 6,7-Isoquinolinediol,1,2,3,4-tetrahydro-1-methyl-, hydrobromide (1:1)
  • (R)-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE

Related Compounds

  • salsolidine hydrochloride
  • Losoxantrone hydrochloride [USAN]
  • Triprolidine hydrochloride
  • ethaniMidaMide hydrochloride
  • Tyrocidine, hydrochloride
  • dodecylamine hydrochloride
  • [1-(3-Chloro-5,6-dimethylpyridazin-4-yl)-3,3-difluorocyclobutyl]methanamine
  • tert-butyl 2-(1,3-dimethyl-1H-pyrazol-4-yl)piperazine-1-carboxylate
  • (1S)-2,2,2-trifluoro-1-(5-nitropyridin-2-yl)ethan-1-ol
  • 1-{2-[6-(Trifluoromethyl)pyridin-3-yl]ethyl}cyclopropan-1-amine
  • Methyl 5-[(1-hydroxycyclopropyl)methyl]furan-2-carboxylate
  • tert-butyl N-[4-(1-amino-4-hydroxycyclohexyl)-3-chlorophenyl]carbamate
  • 3-(aminomethyl)-3-(3-phenyl-1H-pyrazol-4-yl)cyclobutan-1-ol
  • [4,4-Difluoro-1-(isoquinolin-5-yl)cyclohexyl]methanamine
  • 3-(4-Chloro-3-fluorophenyl)-1,1-difluoro-2-methylpropan-2-amine
  • (1-{[4-(Trifluoromethyl)pyridin-3-yl]methyl}cyclopropyl)methanamine
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