3-nitropyridin-2-ol

Suppliers

Names

[ Name ]:
3-nitropyridin-2-ol

[Synonym ]:
3-Nitro-2(1H)-pyridinone
3-NITRO-2-PYRIDONE
MFCD00006270
2-hydroxy-3-nitro-pyridine
2-Hydroxy-3-Nitro
3-nitro-2-pyridino
EINECS 228-709-2
2(1H)-Pyridinone, 3-nitro-
2-Hydroxy-3-nitropyridine
3-nitropyridin-2-ol
hydroxynitropyridine
2-HYDRO-3-NITROPYRIDINE
3-Nitro-2-hydroxypyridine
2-Pyridinol,3-nitro
AURORA KA-2996
3-nitropyridin-2(1H)-one

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
314.7±22.0 °C at 760 mmHg

[ Melting Point ]:
212 °C (dec.)(lit.)

[ Molecular Formula ]:
C₅H₄N₂O₃

[ Molecular Weight ]:
140.097

[ Flash Point ]:
144.1±22.3 °C

[ Exact Mass ]:
140.022186

[ PSA ]:
78.68000

[ LogP ]:
-0.31

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.623

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU7718000

CHEMICAL NAME :: 2-Pyridinol, 3-nitro-

CAS REGISTRY NUMBER :: 6332-56-5

LAST UPDATED :: 199410

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C5-H4-N2-O3

MOLECULAR WEIGHT :: 140.11

WISWESSER LINE NOTATION :: T6NJ BQ CNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 1 umol/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 58,11,1978

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi,Xn

[ Risk Phrases ]:
R36/37/38;R40

[ Safety Phrases ]:
S26-S36-S45-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
UU7718000

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

3-Aminopyridin-2-ol
3-Amino-2-cyanopyridine
2-Chloro-3-nitropyridine
Benzyl (2-oxo-1,2-dihydro-3-pyridinyl)carbamate
ethyl 2-(3-nitro-2-oxopyridin-1-yl)acetate
ETHYL (3-AMINO-2-OXO-1,2-DIHYDROPYRIDYL)ACETATE
2-Bromo-3-pyridinamine
2-Chloro-5-iodo-3-pyridinamine
3-Amino-2-pyridinecarboxamide
2-Chloro-5-iodo-3-nitropyridine

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

5-Azidoepibatidine: an exceptionally potent photoaffinity ligand for neuronal alpha 4 beta 2 and alpha 7 nicotinic acetylcholine receptors.

Bioorg. Med. Chem. Lett. 13(3) , 525-7, (2003)

Racemic 5-azidoepibatidine [(+/-)-1] was synthesized via 5-aminoepibatidine as a candidate photoaffinity ligand with exceptionally high affinity at the mammalian neuronal nicotinic receptors (K(i) val...

85. Nucleophilic displacement reactions in aromatic systems. Part I. Kinetics of the reactions of chloronitropyridines with aromatic amines and with pyridine. Bishop RR, et al.

J. Chem. Soc. , 437-46, (1952)

Nitropyridyl glycosides: new glycosyl donors for enzymatic transglycosylation. Yasukochi T, et al.

Tetrahedron Lett. 40(36) , 6585-89, (1999)