2,4,6-Trichloroaniline
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Names
[ CAS No. ]:
634-93-5
[ Name ]:
2,4,6-Trichloroaniline
[Synonym ]:
2,4,6-Trichlorophenylamine
2,3-DIHYDROBENZO[1,4]DIOXINE-5-CARBONYL CHLORIDE 0.98
Benzenamine, 2,4,6-trichloro-
2,4,6-trichloro-aniline
2,4,6-Trichloroaniline
1-amino-2,4,6-trichlorobenzene
2,4,6-Trichlorobenzenamine
2,4,6-trichloraniline
sym-Trichloroaniline
EINECS 211-219-8
2,4,6-Trichlor-anilin
Aniline,2,4,6-trichloro
s-Trichloroaniline
MFCD00007663
Benzenamine,2,4,6-trichloro
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
258.4±35.0 °C at 760 mmHg
[ Melting Point ]:
75 °C
[ Molecular Formula ]:
C6H4Cl3N
[ Molecular Weight ]:
196.462
[ Flash Point ]:
110.1±25.9 °C
[ Exact Mass ]:
194.940933
[ PSA ]:
26.02000
[ LogP ]:
3.74
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.626
[ Stability ]:
Stable, but may be light or air sensitive. Incompatible with acids, acid chlorides, acid anhydrides, chloroformates, strong oxidizing agents.
[ Water Solubility ]:
<0.1 g/100 mL at 21.5 ºC
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BZ0250000
- CHEMICAL NAME :
- Aniline, 2,4,6-trichloro-
- CAS REGISTRY NUMBER :
- 634-93-5
- BEILSTEIN REFERENCE NO. :
- 0879568
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 14
- MOLECULAR FORMULA :
- C6-H4-Cl3-N
- MOLECULAR WEIGHT :
- 196.46
- WISWESSER LINE NOTATION :
- ZR BG DG FG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2400 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1180 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 36 gm/kg/45D-I
- TOXIC EFFECTS :
- Blood - changes in erythrocyte (RBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - catalases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5200 mg/kg/26W-I
- TOXIC EFFECTS :
- Behavioral - alteration of classical conditioning Blood - methemoglobinemia-carboxyhemoglobin
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 390 gm/kg/78W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 780 gm/kg/78W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors
MUTATION DATA
- TEST SYSTEM :
- Insect - Drosophila melanogaster
- DOSE/DURATION :
- 5 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 211,279,1988
Safety Information
[ Symbol ]:
GHS06, GHS08, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H311-H331-H373-H410
[ Precautionary Statements ]:
P261-P273-P280-P301 + P310-P311-P501
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic;N:Dangerousfortheenvironment;
[ Risk Phrases ]:
R23/24/25;R33;R50/53
[ Safety Phrases ]:
S28-S36/37-S45-S60-S61-S28A
[ RIDADR ]:
UN 2811 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
BZ0250000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
2921420090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921420090
[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Gig. Sanit. (3) , 83-4, (1985)
Wei Sheng Yan Jiu 27(2) , 87-9, (1998)
Trichloroaniline in the air was collected with 50% ethanol and separated with a column OV-17:OV-210 ECD as a detector. The best conditions of sampling and determining were selected through the orthogo...
Chemosphere 73(11) , 1731-6, (2008)
Leaching experiments are performed from clay-pollutant systems in order to evaluate the capability of clays to sequestrate organic pollutants from wastewaters. Reference kaolinite KGa-1b, montmorrillo...