1,1'-piperazine-1,4-diylbisprop-2-en-1-one

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Names

[ Name ]:
1,1'-piperazine-1,4-diylbisprop-2-en-1-one

[Synonym ]:
1,4-bis (acryloyl)piperazine
2-Propen-1-one, 1,1'-(1,4-piperazinediyl)bis-
1,4-DIACRYLYLPIPERAZINE
DIACRYLYL-PIPERAZINE
1,1'-piperazine-1,4-diylbisprop-2-en-1-one
PDA
1,1'-(1,4-Piperazinediyl)bis(2-propen-1-one)
BAP
MFCD00077661
PIP
N,N'-DIACRYLOYLPIPERAZINE
N,N'-Bisacryloylpiperazine
PIPERAZINE DIACRYLAMIDE
1,4-Bis(acryloyl)piperazine

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
434.1±25.0 °C at 760 mmHg

[ Melting Point ]:
91.5-93.5 °C(lit.)

[ Molecular Formula ]:
C₁₀H₁₄N₂O₂

[ Molecular Weight ]:
194.230

[ Flash Point ]:
216.5±15.5 °C

[ Exact Mass ]:
194.105530

[ PSA ]:
40.62000

[ LogP ]:
-1.22

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.517

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29335995

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Piperazine
Acrylyl chloride

DownStream

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Peroxiredoxin I protein, a potential biomarker of hydronephrosis in fetal mice exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

J. Pediatr. Urol. 10(3) , 474-81, (2014)

In previous studies, we established an animal model of human congenital hydronephrosis with exposure of developing mice to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), but the etiopathogenesis is not e...

Urine proteome analysis in Dent's disease shows high selective changes potentially involved in chronic renal damage.

J. Proteomics 130 , 26-32, (2015)

Definition of the urinary protein composition would represent a potential tool for diagnosis in many clinical conditions. The use of new proteomic technologies allows detection of genetic and post-tra...

ECM stiffness primes the TGFβ pathway to promote chondrocyte differentiation.

Mol. Biol. Cell 23 , 3731-42, (2012)

Cells encounter physical cues such as extracellular matrix (ECM) stiffness in a microenvironment replete with biochemical cues. However, the mechanisms by which cells integrate physical and biochemica...

1,1'-(1,4-phenylene)bis(3-(diethylamino)-3-phenylprop-2-en-1-one)
4,4,4-trifluoro-3-(trifluoromethyl)-1-[4-[4,4,4-trifluoro-3-(trifluoromethyl)but-2-enoyl]phenyl]but-2-en-1-one
1-(1,4-dioxaspiro[4.5]decan-8-yl)non-2-en-1-one
1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)prop-2-en-1-one
1-(1,4,7,10,13-pentaoxa-16-azacyclooctadec-16-yl)prop-2-en-1-one
2-Propen-1-one,1-[1,1'-biphenyl]-4-yl-3-(4-methoxyphenyl)-
3-{1-[(oxolan-2-yl)methyl]-1H-pyrazol-4-yl}prop-2-yn-1-amine
3-{1-[(oxan-3-yl)methyl]-1H-pyrazol-4-yl}propanoic acid
4-ethynyl-1-[(oxan-3-yl)methyl]-1H-pyrazole
(2E)-3-{1-[(oxan-3-yl)methyl]-1H-pyrazol-4-yl}prop-2-enoic acid
2-{1-[(oxan-3-yl)methyl]-1H-pyrazol-4-yl}ethan-1-amine
4-iodo-1-[(oxan-3-yl)methyl]-1H-pyrazole
3-{1-[(oxan-3-yl)methyl]-1H-pyrazol-4-yl}propan-1-amine
methyl(3-{1-[(oxan-3-yl)methyl]-1H-pyrazol-4-yl}propyl)amine
2,2,2-trifluoro-1-{1-[(oxan-3-yl)methyl]-1H-pyrazol-4-yl}ethan-1-one
4-{1-[(oxan-3-yl)methyl]-1H-pyrazol-4-yl}piperidine

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