1,1'-piperazine-1,4-diylbisprop-2-en-1-one

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Names

[ CAS No. ]:
6342-17-2

[ Name ]:
1,1'-piperazine-1,4-diylbisprop-2-en-1-one

[Synonym ]:
1,4-bis (acryloyl)piperazine
2-Propen-1-one, 1,1'-(1,4-piperazinediyl)bis-
1,4-DIACRYLYLPIPERAZINE
DIACRYLYL-PIPERAZINE
1,1'-piperazine-1,4-diylbisprop-2-en-1-one
PDA
1,1'-(1,4-Piperazinediyl)bis(2-propen-1-one)
BAP
MFCD00077661
PIP
N,N'-DIACRYLOYLPIPERAZINE
N,N'-Bisacryloylpiperazine
PIPERAZINE DIACRYLAMIDE
1,4-Bis(acryloyl)piperazine

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
434.1±25.0 °C at 760 mmHg

[ Melting Point ]:
91.5-93.5 °C(lit.)

[ Molecular Formula ]:
C10H14N2O2

[ Molecular Weight ]:
194.230

[ Flash Point ]:
216.5±15.5 °C

[ Exact Mass ]:
194.105530

[ PSA ]:
40.62000

[ LogP ]:
-1.22

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.517

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29335995

Synthetic Route

Precursor & DownStream

Precursor

  • Piperazine
  • Acrylyl chloride

DownStream

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Peroxiredoxin I protein, a potential biomarker of hydronephrosis in fetal mice exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

J. Pediatr. Urol. 10(3) , 474-81, (2014)

In previous studies, we established an animal model of human congenital hydronephrosis with exposure of developing mice to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), but the etiopathogenesis is not e...

Urine proteome analysis in Dent's disease shows high selective changes potentially involved in chronic renal damage.

J. Proteomics 130 , 26-32, (2015)

Definition of the urinary protein composition would represent a potential tool for diagnosis in many clinical conditions. The use of new proteomic technologies allows detection of genetic and post-tra...

ECM stiffness primes the TGFβ pathway to promote chondrocyte differentiation.

Mol. Biol. Cell 23 , 3731-42, (2012)

Cells encounter physical cues such as extracellular matrix (ECM) stiffness in a microenvironment replete with biochemical cues. However, the mechanisms by which cells integrate physical and biochemica...


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Related Compounds

  • 1,1'-(1,4-phenylene)bis(3-(diethylamino)-3-phenylprop-2-en-1-one)
  • 4,4,4-trifluoro-3-(trifluoromethyl)-1-[4-[4,4,4-trifluoro-3-(trifluoromethyl)but-2-enoyl]phenyl]but-2-en-1-one
  • 1-(1,4-dioxaspiro[4.5]decan-8-yl)non-2-en-1-one
  • 1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)prop-2-en-1-one
  • 1-(1,4,7,10,13-pentaoxa-16-azacyclooctadec-16-yl)prop-2-en-1-one
  • 2-Propen-1-one,1-[1,1'-biphenyl]-4-yl-3-(4-methoxyphenyl)-
  • (6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl){4-[2-(propan-2-yl)-2H-tetrazol-5-yl]phenyl}methanone
  • N-(6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-1-yl)-2-(1H-tetrazol-1-yl)benzamide
  • 1-[2-(2-methoxyphenyl)ethyl]-N-(2-methyl-1H-benzimidazol-6-yl)-5-oxopyrrolidine-3-carboxamide
  • N-[3-(1-methyl-1H-benzimidazol-2-yl)propyl]-4-(4-oxo-1,2,3-benzotriazin-3(4H)-yl)butanamide
  • N-(4,5-dimethyl-1,3-thiazol-2-yl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxamide
  • N-[2-(1H-benzimidazol-1-yl)ethyl]-1-(1H-tetrazol-1-yl)cyclohexanecarboxamide
  • 2-chloro-N-[2-(3,4-dimethoxyphenyl)ethyl]-5-methyl-1,3-thiazole-4-carboxamide
  • N-(8-chloro-2,3,4,9-tetrahydro-1H-carbazol-1-yl)-2-(2,4,5-trifluorophenyl)acetamide
  • N-(2,6-difluorobenzyl)-4-(1H-pyrazol-1-yl)butanamide
  • 2-[4-(2-methyl-2H-tetrazol-5-yl)phenoxy]-N-(pyridin-2-ylmethyl)acetamide