WAY-100635 (maleate salt)

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Names

[ CAS No. ]:
634908-75-1

[ Name ]:
WAY-100635 (maleate salt)

[Synonym ]:
Cyclohexanecarboxamide, N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-, (2Z)-2-butenedioate (1:1)
N-{2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl}-N-(2-pyridinyl)cyclohexanecarboxamide (2Z)-2-butenedioate (1:1)
N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinylcyclohexanecarboxamide maleate salt
N-{2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)cyclohexanecarboxamide (2Z)-but-2-enedioate (1:1)
N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinylcyclohexanecarboxamide maleate
WAY-100635
WAY100635 maleate salt
WAY-100635 (maleate salt)

Chemical & Physical Properties

[ Boiling Point ]:
594.8ºC at 760 mmHg

[ Molecular Formula ]:
C29H38N4O6

[ Molecular Weight ]:
538.635

[ Flash Point ]:
313.5ºC

[ Exact Mass ]:
538.279114

[ PSA ]:
123.51000

[ LogP ]:
3.54040

[ Storage condition ]:
-20°C

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

LSD but not lisuride disrupts prepulse inhibition in rats by activating the 5-HT(2A) receptor.

Psychopharmacology 208(2) , 179-89, (2010)

Compounds that activate the 5-HT(2A) receptor, such as lysergic acid diethylamide (LSD), act as hallucinogens in humans. One notable exception is the LSD congener lisuride, which does not have halluci...

The selective 5-HT1A antagonist radioligand [3H]WAY 100635 labels both G-protein-coupled and free 5-HT1A receptors in rat brain membranes.

Eur. J. Pharmacol. 288 , 173, (1995)

The tritiated derivative of the novel silent 5-HT1A receptor antagonist WAY 100635 [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl) cyclohexane carboxamide] was tested as a potential ra...

Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist.

Behav. Brain Res. 73 , 337, (1996)

Although considerable progress has been made in characterising the 5-HT1A receptor using agonists, partial agonists or non-selective antagonists, further studies of 5-HT1A receptor function have been ...


More Articles


Related Compounds

  • WAY-100635 Maleate
  • WAY-100635
  • WAY 100635 Hydrochloride
  • BRL 54443 maleate salt
  • NB-598 Maleate salt
  • NoMifensine
  • 2-(2-Methoxybenzamido)-5-phenylthiophene-3-carboxamide
  • 2-(4-Isopropoxybenzamido)-5-phenylthiophene-3-carboxamide
  • N-(3-carbamoyl-5-phenylthiophen-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide
  • 5-Phenyl-2-(2-phenylacetamido)thiophene-3-carboxamide
  • N-(3-carbamoyl-5-phenylthiophen-2-yl)benzo[d]thiazole-6-carboxamide
  • N-(3-carbamoyl-5-phenylthiophen-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide
  • 5-Phenyl-2-(3-(phenylsulfonyl)propanamido)thiophene-3-carboxamide
  • 2-(2-((4-Fluorophenyl)sulfonyl)acetamido)-5-phenylthiophene-3-carboxamide
  • 2-(3-((4-Fluorophenyl)sulfonyl)propanamido)-5-phenylthiophene-3-carboxamide
  • 2-(2-((4-Chlorophenyl)sulfonyl)acetamido)-5-phenylthiophene-3-carboxamide
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