5-Chloro-2-hydroxybenzaldehyde

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Names

[ CAS No. ]:
635-93-8

[ Name ]:
5-Chloro-2-hydroxybenzaldehyde

[Synonym ]:
5-chloro-salicylaldehyde
5-Chlor-2-hydroxybenzolcarbaldehyd
Benzaldehyde, 5-chloro-2-hydroxy-
5-Chloro-2-hydroxybenzaldehyde
5-Chlorosalicylaldehyde
EINECS 211-244-4
MFCD00003331

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
228.8±20.0 °C at 760 mmHg

[ Melting Point ]:
100-102 °C(lit.)

[ Molecular Formula ]:
C7H5ClO2

[ Molecular Weight ]:
156.566

[ Flash Point ]:
92.2±21.8 °C

[ Exact Mass ]:
155.997803

[ PSA ]:
37.30000

[ LogP ]:
2.57

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.632

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VN5450000
CHEMICAL NAME :
Salicylaldehyde, 5-chloro-
CAS REGISTRY NUMBER :
635-93-8
BEILSTEIN REFERENCE NO. :
0636632
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C7-H5-Cl-O2
MOLECULAR WEIGHT :
156.57
WISWESSER LINE NOTATION :
VHR BQ EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#05073

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335-H400

[ Precautionary Statements ]:
P261-P273-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25-S36/37/39

[ RIDADR ]:
UN2811/6.1/PG III

[ WGK Germany ]:
3

[ RTECS ]:
VN5450000

[ HS Code ]:
2913000090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Salicylaldehyde
  • Formaldehyde
  • 4-Chlorophenol
  • Aminoform
  • 4-Chloro-2-methylphenol
  • Chloroform
  • Trioctylamine
  • Water
  • 5-chlorosalicylic acid

DownStream

  • 4-(5-chloro-1-benzofuran-2-yl)-7-methoxychromen-2-one
  • 6-chloro-2-naphthalen-1-yl-3-nitro-2H-chromene
  • 4-(5-chloro-1-benzofuran-2-yl)-6-methoxychromen-2-one
  • 6-chloro-4-(5-chloro-1-benzofuran-2-yl)chromen-2-one
  • 5-chlorosalicylic acid
  • 6-CHLORO-2H-1-BENZOPYRAN-3-CARBONYL CHLORIDE
  • ETHANONE, 1-(5-BROMO-2-BENZOFURANYL)-
  • 5-Chloro-2-methoxybenzonitrile
  • 2-(4-chloro-2-formylphenoxy)acetic acid
  • EM20-25

Customs

[ HS Code ]: 2913000090

[ Summary ]:
HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%

Articles

Palladium(0)-mediated C-H bond activation of N-(naphthyl)salicylaldimine and related ligands: utilization of the resulting organopalladium complexes in catalytic C-C and C-N coupling reactions.

Dalton Trans. 44 , 13615-32, (2015)

N-(Naphthyl)-4-R-salicylaldimines (R = OCH(3), H and Cl; H(2L)(1)-H(2)L(3)) and 2-hydroxy-N-(naphthyl)naphthaldimine (H(2)L(4)) readily undergo, upon reaction with Na(2)[PdCl(4)] in the presence of tr...

Structural, spectroscopic and DFT study of 4-methoxybenzohydrazide Schiff bases. A new series of polyfunctional ligands.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 137 , 692-700, (2015)

Five Schiff bases obtained from condensation of 4-methoxybenzohydrazide with related aldehydes, namely o-vanillin, vanillin, 5-bromovanillin, 5-chlorosalicylaldehyde and 5-bromosalicylaldehyde were pr...

New ruthenium(II) carbonyl complexes bearing disulfide Schiff base ligands and their applications as catalyst for some organic transformations.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 129 , 352-8, (2014)

Schiff base disulfide ligands (H2L(1-6)) were synthesized from the condensation of cystamine with salicylaldehyde(H2L(1)), 5-chlorosalicylaldehyde(H2L(2)), o-vanillin(H2L(3)), 2-hydroxyacetophenone(H2...


More Articles

Related Compounds

  • 3-bromo-5-chloro-2-hydroxybenzaldehyde
  • 3-methyl-5-chloro-2-hydroxybenzaldehyde
  • 4-tert-Butyl-5-chloro-2-hydroxybenzaldehyde
  • 5-chloro-2-hydroxybenzaldehyde dimethyl acetal
  • 3-(2,4,6-trimethylphenylimino)methyl-5-chloro-2-hydroxybenzaldehyde
  • 5-Chloro-2-fluoro-4-hydroxybenzaldehyde
  • 1-(Cyclobutylmethyl)-1,4-diazepane
  • 8,8-Dimethyl-1,9-dioxa-4-azaspiro[5.5]undecane
  • 1-[(Dipropylcarbamoyl)methyl]azetidine-3-carboxylic acid
  • 1-(Pyridin-3-ylmethyl)azetidine-3-carboxylic acid
  • N-(4-acetyl-1,3-thiazol-2-yl)-2,2-dimethylpropanamide
  • 2-ethyl-N-(prop-2-yn-1-yl)butanamide
  • N-methoxy-N,1,3,5-tetramethyl-1H-pyrazole-4-carboxamide
  • N-(Cyclopropylmethyl)-2-(4-(trifluoromethoxy)phenyl)ethanamine
  • 3-Amino-1-[1-(4-fluorophenyl)ethyl]pyrrolidin-2-one
  • 4-(aminomethyl)-N,N-diethylthiophene-2-sulfonamide
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