cefotaxime

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Names

[ CAS No. ]:
63527-52-6

[ Name ]:
cefotaxime

[Synonym ]:
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)-
Cefotaxime
(6R,7R)-3-(Acetoxymethyl)-7-{[(2-amino-1,3-thiazol-4-yl)(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Zariviz
Cefabol
Cefotaxima acid
EINECS 264-299-1
Cephotaxime

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Melting Point ]:
162-163℃

[ Molecular Formula ]:
C16H17N5O7S2

[ Molecular Weight ]:
455.466

[ Exact Mass ]:
455.056946

[ PSA ]:
227.05000

[ LogP ]:
1.20

[ Index of Refraction ]:
1.779

[ Storage condition ]:
2-8℃

Safety Information

[ HS Code ]:
3003201100

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (6R,7R)-3-(acetyloxymethyl)-7-[[(2E)-2-[2-[(2-chloroacetyl)amino]-1,3-thiazol-4-yl]-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7R)-3-(acetoxymethyl)-7-(4-chloro-2-(methoxyimino)-3-oxobutanamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • S-2-Benzothiazolyl 2-amino-alpha-(methoxyimino)-4-thiazolethiolacetate
  • 7-Aminocephalosporanic acid
  • (Z)-4-CHLORO-2-(METHOXYIMINO)-3-OXOBUTANOIC ACID
  • Ethyl 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate
  • (Z)-γ-bromo-β-oxo-α-methoxyiminobutyric acid ethyl ester
  • ethyl (2Z)-2-methoxyimino-2-[2-(tritylamino)-1,3-thiazol-4-yl]acetate

DownStream

  • ceftiofur
  • Cefpodoxime Proxetil
  • Cefpirome
  • Cefquinome
  • cefotaxime sodium

Customs

[ HS Code ]: 3003201100

Articles

Effects of decontamination of the digestive tract and oropharynx in intensive care unit patients on 1-year survival.

Am. J. Respir. Crit. Care Med. 188(1) , 117-20, (2013)

National surveillance study on carbapenem non-susceptible Klebsiella pneumoniae in Taiwan: the emergence and rapid dissemination of KPC-2 carbapenemase.

PLoS ONE 8(7) , e69428, (2013)

The global spread and increasing incidence of carbapenem non-susceptible Klebsiella pneumoniae (CnSKP) has made its treatment difficult, increasing the mortality. To establish nationwide data on CnSKP...

Synthesis, characterization, and antimicrobial activity of poly(acrylonitrile-co-methyl methacrylate) with silver nanoparticles.

Appl. Biochem. Biotechnol. 171(3) , 643-54, (2013)

Nanotechnology is expected to open some new aspects to fight and prevent diseases using atomic-scale tailoring of materials. The main aim of this study is to biosynthesize silver nanoparticles (AgNPs)...


More Articles

Related Compounds

  • cefotaxime
  • cefotaxime
  • cefotaxime
  • Cefotaxime Na
  • cefotaxime 1β-oxide
  • Desacetylcefotaxime
  • 1-(5-Chloro-2-methylphenyl)-4-{[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]methyl}piperazine
  • 4-Tert-butyl-6-[4-(cyclopropanesulfonyl)piperazin-1-yl]-2-(methylsulfanyl)pyrimidine
  • 5-Chloro-2-[4-(2-chlorophenyl)piperazin-1-yl]pyrimidine
  • 5-[4-(6-Cyclobutyl-2-cyclopropylpyrimidin-4-yl)piperazin-1-yl]pyridine-2-carbonitrile
  • 4-[4-(cyclopropanesulfonyl)piperazin-1-yl]-6-(4-methyl-1H-pyrazol-1-yl)pyrimidine
  • 4-{[4-(2-Cyclopropyl-6-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}benzonitrile
  • 1-(2,3-Dichlorophenyl)-4-{[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]methyl}piperazine
  • 1-(2,3-Dichlorophenyl)-4-[(pyridin-4-yl)methyl]piperazine
  • 3-[2-(Cyclopropylamino)pyrimidin-5-yl]-5-(trifluoromethyl)phenol
  • 2-(2-chloro-6-fluorophenyl)-N-[(pyrazin-2-yl)methyl]acetamide
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