Darunavir Ethanolate

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Names

[ CAS No. ]:
635728-49-3

[ Name ]:
Darunavir Ethanolate

[Synonym ]:
DARUNAVIR ETHANOLATE(PREZISTA) TMC114
(3R,3aS,6aR)-Hexahydrofuro[2,3-b]fur-3-yl-[(1S,2R)-3-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-1-benzyl-2-hydroxypropyl]carbamat-ethanol(1:1)
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2R)-3-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-1-benzyl-2-hydroxypropyl]carbamate - ethanol (1:1)
[(1S,2R)-3-{[(4-aminophényl)sulfonyl](2-méthylpropyl)amino}-1-benzyl-2-hydroxypropyl]carbamate de (3R,3aS,6aR)-hexahydrofuro[2,3-b]fur-3-yle - éthanol (1:1)
Darunavir Ethanolate
(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](isobutyl)amino}-3-hydroxy-1-phenyl-2-butanyl]carbamate - ethanol (1:1)
Carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester, compd. with ethanol (1:1)
carbamic acid, [(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester, compd. with ethanol (1:1)
UNII-33O78XF0BW
Darunavir Ethanolate(Prezista)
Darunavir (Ethanolate)
DARUNAVIR THANOLATE

Chemical & Physical Properties

[ Molecular Formula ]:
C29H43N3O8S

[ Molecular Weight ]:
593.732

[ Exact Mass ]:
593.277100

[ PSA ]:
169.03000

[ LogP ]:
4.42680

[ Storage condition ]:
-20℃

Safety Information

[ HS Code ]:
29334900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethanol
  • 4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide
  • (2R,3S)-3-(tert-Butoxycarbonyl)aMino-1,2-epoxy-4-phenylbutane
  • TERT-BUTYL ((2S,3R)-3-HYDROXY-4-(N-ISOBUTYL-4-NITROPHENYLSULFONAMIDO)-1-PHENYLBUTAN-2-YL)CARBAMATE
  • tert-Butyl [(1S,2R)-1-Benzyl-2-hydroxy-3-(isobutylamino)propyl]carbamate
  • TERT-BUTYL ((2S,3R)-4-(4-AMINO-N-ISOBUTYLPHENYLSULFONAMIDO)-3-HYDROXY-1-PHENYLBUTAN-2-YL)CARBAMATE
  • erythro-N-Boc-D-phenylalanine epoxide

DownStream

Related Compounds

  • Darunavir ethanolate
  • Darunavir
  • Darunavir-d9
  • [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate,hydrate
  • Darunavir
  • Darunavir O-β-D-Glucuronide