4-Chloro-2,5-Dimethoxyaniline

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Names

[ CAS No. ]:
6358-64-1

[ Name ]:
4-Chloro-2,5-Dimethoxyaniline

[Synonym ]:
2-Chloro-3,6-dimethoxyaniline
EINECS 228-782-0
Benzenamine, 2-chloro-3,6-dimethoxy-
MFCD00014893
4-Chloro-2,5-Dimethoxyaniline
Benzenamine, 4-chloro-2,5-dimethoxy-
2,5-Dimethoxy-4-chloroaniline

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
290.1±35.0 °C at 760 mmHg

[ Melting Point ]:
118-120 °C(lit.)

[ Molecular Formula ]:
C8H10ClNO2

[ Molecular Weight ]:
187.624

[ Flash Point ]:
129.3±25.9 °C

[ Exact Mass ]:
187.040009

[ PSA ]:
44.48000

[ LogP ]:
2.20

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.556

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BX1225000
CHEMICAL NAME :
Aniline, 4-chloro-2,5-dimethoxy-
CAS REGISTRY NUMBER :
6358-64-1
BEILSTEIN REFERENCE NO. :
0880445
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H10-Cl-N-O2
MOLECULAR WEIGHT :
187.64
WISWESSER LINE NOTATION :
1OR BZ EG DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
BX1225000

[ HS Code ]:
2922299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Chloro-2,5-dimethoxynitrobenzene
  • 2,5-Dimethoxy-4-nitroaniline
  • 2,5-dimethoxychlorobenzene
  • Chlorohydroquinone

DownStream

  • 4-CHLORO-2,5-DIMETHOXYPHENYL ISOTHIOCYANATE
  • Naphthol AS-LC
  • N-(4-chloro-3,6-dioxocyclohexa-1,4-dien-1-yl)benzamide
  • 1-chloro-4-(4-chloro-2,5-dimethoxyphenyl)-2,5-dimethoxybenzene
  • [[4-(4-bromobenzoyl)diazenylphenyl]amino] 3-nitrobenzoate
  • 1-Chloro-4-iodo-2,5-dimethoxybenzene
  • 2-amino-5-chloro-4-methoxyphenol

Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • 4-chloro-2,5-dimethoxyaniline,hydrochloride
  • 4-chloro-2,5-diethoxyaniline
  • 4-Chloro-2,5,7-trimethylquinoline
  • 4-chloro-2,5-bis-trichloromethyl-benzophenone
  • 4-Chloro-2,5-dimethylquinazoline
  • (4-Chloro-2,5-dimethylphenyl)hydrazine
  • 2-{[3-(3,5-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-(propan-2-yl)acetamide
  • N-(2-methoxyphenyl)-2-(7-methyl-4-oxo-9-phenylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 4,5,7-Trichloro-3-methyl-2-benzofurancarboxylic acid
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • Ethyl 6-oxo-1-(p-tolyl)-4-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)-1,6-dihydropyridazine-3-carboxylate